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Job DescriptionP15498
Confidence100.00%DateFri May 25 09:26:45 BST 2012
Rank10Aligned Residues315
% Identity23%Templatec1x86A_
PDB info PDB header:signaling protein/membrane proteinChain: A: PDB Molecule:rho guanine nucleotide exchange factor 12; PDBTitle: crystal structure of the dh/ph domains of leukemia-associated rhogef2 in complex with rhoa
Resolution3.22 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   189190.........200.........210.........220...... ...230.........240.........250.........260...
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Query Sequence  MTEYDKRCCCLREIQQTEEKYTDTLGSIQQHFLKPLQR. . FLKPQDIEIIFINIEDLLRVHTHFLKEMKEALGTPGA. . .
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Template Sequence  KPCEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQLHIGLNEQMKAVRKRNETSVI
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   782.......790.........800.........810.........820.........830.........840.........850.........860.
 
   264.....270.... .....280.........290.........300.........310.........320.........330.......
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Query Sequence  ANLYQVFIKYK. . . . . . ERFLVYGRYCSQVESASKHLDRVAAAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYH
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Template Sequence  DQIGEDLLTWFSGPGEEKLKHAAATFCSNQPFALEMIKSRQKKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYP
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TSGGGTT

TT
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   862.......870.........880.........890.........900.........910.........920.........930.........940.
 
   338.340.........350.........360.........370.........380.........390......... 400....
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Query Sequence  LLLQELVKHTQEAMEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLAH. . . . . . . . . . . . . YGRPK
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Template Sequence  LLLDNIAKYTEWPTEREKVKKAADHCRQILNFVNQAVKEAENKQRLEDYQRRLDTSSLKLSEYPNVEELRNLDLTKRKMI
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T
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   942.......950.........960.........970.........980.........990.........1000.........1010.........1020.
 
   405....410.........420.........430.........440 .........450.........460.........470........
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Query Sequence  IDGELKITSVERRSKMDRYAFLLDKALLICKRRGDS. . . . . . YDLKDFVNLHSFQVRDDSSGDRDNKKWSHMFLLIEDQG
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Template Sequence  HEGPLVWKV. NRDKTIDLYTLLLEDILVLLQKQDDRLVLRCHSTFSPVIKLSTVLVRQVATDNK. . . . . ALFVISMSDNG
Template Known Secondary structure  S.
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   1022.......1030 .........1040.........1050.........1060.........1070.........1080.... .....1090.....
 
   479480.........490.........500.........
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Query Sequence  AQGYELFFKTRELKKKWMEQFEMAISNIYPE
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Template Sequence  AQIYELVAQTVSEKTVWQDLICRMAASVKEQ
Template Known Secondary structure  B


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   1107..1110.........1120.........1130.......
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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