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Job DescriptionP06239
Confidence100.00%DateWed May 9 17:41:23 BST 2012
Rank59Aligned Residues259
% Identity36%Templatec3fupB_
PDB info PDB header:transferaseChain: B: PDB Molecule:tyrosine-protein kinase jak2; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   236...240.........250.........260...... ...270......... 280.........290.........300.........
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Query Sequence  DEWEVPRETLKLVERLGAGQFGEVWMGYYNG. . . . . HTKVAVKSLKQGS. MSPDAFLAEANLMKQLQHQRLVRLYAVVTQ
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Template Sequence  DPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCY.
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   840.........850.........860.........870.........880.........890.........900.........910........
 
   310.........320.........330.........340.........350.........360.........370.........380.........
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Query Sequence  EPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLI
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Template Sequence  SNLKLIMEYLPYGSLRDYLQKHK. ERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVL
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TT
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   919920.........930.........940. ........950.........960.........970.........980.........990.......
 
   390.........400.........410.........420.........430.........440... ......450...
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Query Sequence  EDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPG. . . . . . . . . . . . . . . . MTNPEVIQNL
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Template Sequence  PQDKEKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFT. YIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELL
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   1002.......1010.........1020.........1030.........1040....... ..1050.........1060.........1070.........1080
 
   454.....460.........470.........480.........490.......
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Query Sequence  ERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDF
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Template Sequence  KNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQI
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   1083......1090.........1100.........1110.........1120......
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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