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Job DescriptionP06239
Confidence100.00%DateWed May 9 17:41:23 BST 2012
Rank45Aligned Residues257
% Identity37%Templatec3eygA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes
Resolution1.90 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   236...240.........250.........260..... ....270.........280.........290.........300.........310
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Query Sequence  DEWEVPRETLKLVERLGAGQFGEVWMGYYN. . . . . GHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQE
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Template Sequence  DPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLK. . . PHIADLKKEIEILRNLYHENIVKYKGICTEN
Template Known Secondary structure 
TTS

GGG
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TTSSS
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T


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   866...870.........880.........890.........900.........910. ........920.........930.........940..
 
   311........320.........330.........340.........350.........360.........370.........380.........390
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Query Sequence  PIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIE
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Template Sequence  GIKLIMEFLPSGSLKEYLPKNK. NKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIE
Template Known Secondary structure 


TT
BTGGGT.TT

TT
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SGGGTT


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   951........960.........970.. .......980.........990.........1000.........1010.........1020.........
 
   391........400.........410.........420.........430.........440. ........450.....
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Query Sequence  DNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPY. . . . . . . . . . . . . . . PGMTNPEVIQNLER
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Template Sequence  TDKETVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLT. YCDSDSSPMALFLKMIGPTHGQMTVTRLVNTLKE
Template Known Secondary structure  TT



S

TT

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T.TT
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   1030.........1040.........1050.........1060.........1070.... .....1080.........1090.........1100........
 
   456...460.........470.........480.........490.......
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Query Sequence  GYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDF
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Template Sequence  GKRLPCPPNCPDEVYQLMRKCWEFQPSNRTSFQNLIEGFEAL
Template Known Secondary structure  T





TT

T

SSGGGS

TT
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   1111........1120.........1130.........1140.........1150..
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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