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Job DescriptionP06239
Confidence100.00%DateWed May 9 17:41:23 BST 2012
Rank56Aligned Residues252
% Identity35%Templatec3d4qA_
PDB info PDB header:transferaseChain: A: PDB Molecule:b-raf proto-oncogene serine/threonine-protein kinase; PDBTitle: pyrazole-based inhibitors of b-raf kinase
Resolution2.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   236...240.........250.........260.........270.........280... ......290.........300.........310..
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Query Sequence  DEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPD. . . AFLAEANLMKQLQHQRLVRLYAVVTQEPI
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Template Sequence  DDWEIPDGQITVGQRIGSGSFGTVYKGKWHGD. . VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQL
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B

TT

TTSSS..

SSS

TT


TTB


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   448.450.........460.........470......... 480.........490.........500.........510.........520.....
 
   313......320.........330.........340.........350.........360.........370.........380.........390..
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Query Sequence  YIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDN
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Template Sequence  AIVTQWCEGSSLYHHLHI. IETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVLSG.
Template Known Secondary structure 

SS
BT.S




TT
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SGGGTTT


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   526...530.........540... ......550.........560.........570.........580.........590.........600...
 
   393......400.........410...... ...420.........430.........440........ .450.........460 ....
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Query Sequence  EYTAREGAKFPIKWTAPEAINYGT. . . FTIKSDVWSFGILLTEIVTHGRIPYPGMTNPE. VIQNLERGYRMV. . . . RPDN
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Template Sequence  . . . . . . . . . . SILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMT. GQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSN
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TT

TT
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S.SS
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TT
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   616...620.........630.........640.........650. ........660.........670.........680....
 
   465....470.........480.........490.........500..
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Query Sequence  CPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTATE
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Template Sequence  CPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLP
Template Known Secondary structure  S
T
SSGGGS

T

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   685....690.........700.........710.........720..
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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