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Job DescriptionP06239
Confidence100.00%DateWed May 9 17:41:23 BST 2012
Rank7Aligned Residues369
% Identity34%Templatec2ozoA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: autoinhibited intact human zap-70
Resolution2.60 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   120.........130.........140.........150.........160.........170.........180.........190.........
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Query Sequence  NSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITF
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Template Sequence  DPAAHLPFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVR. . . . . FHHFPIERQLNGTYAIAGGKAH
Template Known Secondary structure 
TTSS
TTB
BS

TTT

TT
TTBTT
TT.....
TTS
TTS

B
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   3......10.........20.........30.........40.........50..... ....60.........70.......
 
   200.........210.........220.........230....
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Query Sequence  PGLHELVRHYTNASDGLCTRLSRPCQTQKPQKPWW. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  CGPAELCEFYSRDPDGLPCNLRKPCNRPSGLEPQPGVFDCLRDAMVRDYVRQTWKLEGEALEQAIISQAPQVEKLIATTA
Template Known Secondary structure  SSTS

TTSSS


SB



TT


B




TTS
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   78.80.........90.........100.........110.........120.........130.........140.........150.......
 
  
Predicted Secondary structure  ................................................................................
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
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Template Sequence  HERMPWYHSSLTREEAERKLYSGAQTDGKFLLRPRKEQGTYALSLIYGKTVYHYLISQDKAGKYCIPEGTKFDTLWQLVE
Template Known Secondary structure  TTTSTTB
TT

SSS


TT

SSTTTT
TT


TTS
SS
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   158.160.........170.........180.........190.........200.........210.........220.........230.......
 
   235....240.........250.........260........ .270....
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . EDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHT. . . KVAVKS
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Template Conservation   
      
   
                                        

 
 

 
             



 
Template Sequence  YLKLKADGLIYCLKEACPNMDTSVFESPFSDPEELKDKKLFLKRDNLLIADIELGCGNFGSVRQGVYRMRKKQIDVAIKV
Template Known Secondary structure 

TT
SS


SB






S
SSSSS
S
SS



SB

TTS
SSS
SS
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   238.240.........250.........260.........270.........280.........290.........300.........310.......
 
   275....280 .........290.........300.........310.........320.........330.........340.........350..
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Query Sequence  LKQGSM. . SPDAFLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGM
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Template Sequence  LKQGTEKADTEEMMREAQIMHQLDNPYIVRLIGVCQAEALMLVMEMAGGGPLHKFLVGKRE. EIPVSNVAELLHQVSMGM
Template Known Secondary structure 




SSTTTT


TTB

SSS

TT
BTT
TT.TS
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   371........380.........390.........400.........410.........420.........430. ........440.........
 
   353......360.........370.........380.........390.........400.........410.........420.........430..
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Query Sequence  AFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTE
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Template Sequence  KYLEEKNFVHRNLAARNVLLVNRHYAKISDFGLSKAL. . . . . . . . . . . . GPLKWYAPECINFRKFSSRSDVWSYGVTMWE
Template Known Secondary structure  TT


S

SGGGTT


STTTT
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TTS




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   450.........460.........470.........480...... ...490.........500.........510.......
 
   433......440.........450.........460.........470.........480.........490.........500......
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Query Sequence  IVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTATEGQYQ
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Template Conservation    
 
  
            
        
   
     

  
    
  

    
   
            
Template Sequence  ALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYALMSDCWIYKWEDRPDFLTVEQRMRACYYSLASKVE
Template Known Secondary structure  TTS

TTTT

STT





TT

TT
SSTTTS

S
S

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   532.......540.........550.........560.........570.........580.........590.........600.....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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