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Job DescriptionP06239
Confidence100.00%DateWed May 9 17:41:23 BST 2012
Rank17Aligned Residues265
% Identity43%Templatec2ivsA_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase receptor PDBTitle: crystal structure of non-phosphorylated ret tyrosine kinase2 domain
Resolution2.00 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   236...240.........250.........260.... .....270.........280... ......290.........300.......
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Query Sequence  DEWEVPRETLKLVERLGAGQFGEVWMGYY. . . . . . NGHTKVAVKSLKQGSMSPD. . AFLAEANLMKQLQHQRLVRLYAVV
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Template Sequence  PKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGAC
Template Known Secondary structure  TTTB

GGG
SSSTGGG
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TT

TT


TTB

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   715....720.........730.........740.........750.........760.........770.........780.........790....
 
   308. 310.........320.........330... ......340.........350.........360.........370.........380
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Query Sequence  TQ. EPIYIITEYMENGSLVDFLKTPSG. . . . . . IKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKI
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Template Sequence  SQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLRALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKI
Template Known Secondary structure 
SSSS


TT
BTTTSTT


TT



SGGGTTT
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   795....800.........810.........820.........830.........840.........850.........860.........870....
 
   381....... .390.........400.........410.........420.........430.........440.........450.........
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Query Sequence  ADFGLARL. IEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRM
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Template Sequence  SDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRM
Template Known Secondary structure 


TT

TTTS

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GGG



TTS

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   891........900.........910.........920.........930.........940.........950.........960.........970
 
   460.........470.........480.........490.........500
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Query Sequence  VRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTA
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Template Sequence  ERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVK
Template Known Secondary structure 


TT

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T
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   971........980.........990.........1000.........1010.
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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