|   |   |
245 | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | |
. | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | |
|
|
|
. | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | |
. | 310 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  | . |
|
|
|  |  |  |  |  |  |
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | K | L | V | E | R | L | G | A | G | Q | F | G | E | V | W | M | G | Y | Y | N | . |
G | H | T | K | V | A | V | K | S | L | K | Q | G | S | M | S | P | D | A | . |
. |
. |
. |
F | L | A | E | A | N | L | M | K | Q | L | Q | H | Q | R | L | V | R | L | Y | A | V | V | T | . |
Q | E | P | I | Y | I | I | T | E | Y |
| Query Conservation |   |
  |   |
|   |   |   |
|
|   |
|   |
|
|   |
|   |   |
|   |   |   | . |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   | . | . | . | . |
|   |   |
|   |   |   |
|   |   |
|   |
|   |
|
|
|   |
|   |
|   |   |   | . |   |   |   |   |   |
|
|   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |   |   |   |
|
|   |
|   |   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
Y | R | L | R | R | L | V | G | R | G | G | X | G | D | V | Y | E | A | E | D | T | V | R | E | R | I | V | A | L | K | L | X | S | E | T | L | S | S | D | P | V | F | R | T | R | X | Q | R | E | A | R | T | A | G | R | L | Q | E | P | H | V | V | P | I | H | D | F | G | E | I | D | G | Q | L | Y | V | D | X | R | L |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |
| S | S |
|  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |  |
| T | T | T | T | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| T | T | B |
|
|  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |
|
|
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
16 | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . |
|   |
|   |   |
319 | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
M | E | N | G | S | L | V | D | F | L | K | T | P | S | G | I | K | L | T | I | N | K | L | L | D | M | A | A | Q | I | A | E | G | M | A | F | I | E | E | R | N | Y | I | H | R | D | L | R | A | A | N | I | L | V | S | D | T | L | S | C | K | I | A | D | F | G | L | A | R | L | I | E | D | N | E | Y | T | A | R | E |
| Query Conservation |   |
  |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |
|
|
|   |   |   |
|
|
|
|
|
|
|   |   |
|
|
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Template Sequence |   |
I | N | G | V | D | L | A | A | X | L | R | R | Q | G | . |
. |
P | L | A | P | P | R | A | V | A | I | V | R | Q | I | G | S | A | L | D | A | A | H | A | A | G | A | T | H | R | D | V | K | P | E | N | I | L | V | S | A | D | D | F | A | Y | L | V | D | F | G | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
| Template Known Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  | T |
| . | . | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
|
|
| G | G | G |  |  |  |
| G | G | G |
|  |  |  |
| S | S | B |
| . | . | . | . | . | . | . | . | . | . | . | . | . |
| Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
96 | . | . | . | 100 | . | . | . | . | . | . | . | . | . | |
|
110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | |
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|   |   |
399 | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | |
|
. | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
G | A | K | F | P | I | K | W | T | A | P | E | A | I | N | Y | G | T | F | T | I | K | S | D | V | W | S | F | G | I | L | L | T | E | I | V | T | H | G | R | I | P | Y | P | G | M | T | N | P | E | V | I | Q | N | L | E | R | G | Y | R | M | V | . |
. |
R | P | D | N | C | P | E | E | L | Y | Q | L | M | R | L | C |
| Query Conservation |   |
  |   |   |   |
|   |   |
|   |
|
|
|   |
|   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |
|   |   | . | . |   |
|   |   |   |
|   |   |
|   |   |
|
|   |   |
|
| Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
. | . | . |   |   |   |   |   |   |   |
|
|   |   | . | . | . | . |   |   |   |   |
|
|
|
|
|
|
|   |
|
|
|
|
|   |
| . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
| Template Sequence |   |
. |
. |
. |
G | T | L | Y | Y | X | A | P | E | R | F | . |
. |
. |
. |
S | E | Y | R | A | D | I | Y | A | L | T | C | V | L | Y | E | C | L | T | . |
G | S | P | P | Y | Q | G | D | Q | L | S | V | X | G | A | H | I | N | Q | A | I | P | R | P | S | T | V | R | P | G | I | P | V | A | F | D | A | V | I | A | R | G |
| Template Known Secondary structure |   |
. | . | . |
|
| T | T | S |
|
| G | G | G | G | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| S | S |
| S | S |  |  |  |  |  |  |  |  |  | T | S |
|
|
|
| G | G | G | T | S | T | T |
|
| T |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
. | . | . |
|
|
|
|
|
|
|
|
|  |  | . | . | . | . |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|
177 | . | . | 180 | . | . | . | . | . | . | . | |
|
|
|
. | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | |
. | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . |
|   |
|   |   |
477 | . | . | 480 | . | . | . | . | |
. | . | . | . | . | 490 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|  |  |  |
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
W | K | E | R | P | E | D | R | . |
P | T | F | D | Y | L | R | S | V | L | E | D | F |
| Query Conservation |   |
  |   |   |
|
|   |   |
| . |
|
|   |   |   |
|   |   |   |
|
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |
|
|   |   |
|   |   |
|
|   |
|
|   |   |   |
|   |   |   |
| Template Sequence |   |
X | A | K | N | P | E | D | R | Y | V | T | C | G | D | L | S | A | A | A | H | A | A |
| Template Known Secondary structure |   |
S |
| S | S | G | G | G | S |
| S | S |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
253 | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . |
|   |