|   |   |
239 | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | |
. | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | V | P | R | E | T | L | K | L | V | E | R | L | G | A | G | Q | F | G | E | V | W | M | G | Y | Y | N | . |
G | H | T | K | V | A | V | K | S | L | K | Q | G | S | M | S | P | D | A | F | L | A | E | A | N | L | M | K | Q | L | Q | H | Q | R | L | V | R | L | Y | A | V | V | T | Q | E | P | I | Y | I | I | T | E |
| Query Conservation |   |
|
|   |   |   |   |   |   |
|   |   |   |
|
|   |
|   |
|
|   |
|   |   |
|   |   |   | . |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|   |
|   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |
|
|   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |
|   |   |   |   |
|   |   |   |   |
|
|
|   |
|   |   |   |   | . | . | . | . | . |   |   |   |
|
|   |   |
|   |   |
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
| Template Sequence |   |
K | A | L | R | D | E | Y | I | M | S | K | T | L | G | S | G | A | C | G | E | V | K | L | A | F | E | R | K | T | C | K | K | V | A | I | K | I | I | S | K | R | N | . |
. |
. |
. |
. |
V | E | T | E | I | E | I | L | K | K | L | N | H | P | C | I | I | K | I | K | N | F | F | D | A | E | D | Y | Y | I | V | L | E |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
| T | T | B |
|
|  |  |  |  |  |  | S | S |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|  |  |  | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
214 | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . |
|   |
|   |   |
318 | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | |
|
|
. | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Y | M | E | N | G | S | L | V | D | F | L | K | T | P | S | G | I | K | L | T | I | N | K | L | L | D | M | A | A | Q | I | A | E | G | M | A | F | I | E | E | R | N | Y | I | H | R | D | L | R | A | A | N | I | L | V | S | D | . |
. |
. |
T | L | S | C | K | I | A | D | F | G | L | A | R | L | I | E | D | N | E | Y |
| Query Conservation |   |
  |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |
|
|
|   |   |   |
|
|
|
|
|
|
|   |   |
|
|
|   |   |   | . | . | . |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |
|   |
|   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
L | M | E | G | G | E | L | F | D | K | V | . |
. |
V | G | N | K | R | L | K | E | A | T | C | K | L | Y | F | Y | Q | M | L | L | A | V | Q | Y | L | H | E | N | G | I | I | H | R | D | L | K | P | E | N | V | L | L | S | S | Q | E | E | D | C | L | I | K | I | T | D | F | G | H | S | K | I | L | G | E | T | S | L |
| Template Known Secondary structure |   |
|
| T | T |
| B | G | G | G | G | T | . | . |
| T | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |
|
|
|
|
| G | G | G |  |  |  | S | S | S | S | S | S |
|
|  |  |  |
|
|
| T | T |
|  |  |
|
|
|  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
303 | . | . | . | . | . | . | 310 | . | . | . | |
|
. | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 |
|   |
|   |   |
395 | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | |
|
|
. | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | |
. | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | |
|
|
. | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
| . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
| Query Sequence |   |
T | A | R | E | G | A | K | F | P | I | K | W | T | A | P | E | A | I | N | Y | . |
. |
. |
G | T | F | T | I | K | S | D | V | W | S | F | G | I | L | L | T | E | I | V | T | H | G | R | I | P | Y | P | . |
G | M | T | N | P | E | V | I | Q | N | L | E | R | G | Y | R | M | V | R | P | . |
. |
. |
D | N | C | P | E |
| Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |
|   |
|
|
|   |
|   |   | . | . | . |   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |
|   |
|   |   |
|   |   | . |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |
|   |   |   |
| . | . | . |   |   |   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   | . | . |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|   |
| . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
| Template Sequence |   |
M | R | T | L | C | G | T | P | T | . |
. |
Y | L | A | P | E | V | L | V | S | V | G | T | A | G | Y | N | R | A | V | D | C | W | S | L | G | V | I | L | F | I | C | L | S | . |
G | Y | P | P | F | S | E | H | R | T | Q | V | S | L | K | D | Q | I | T | S | G | K | Y | N | F | I | P | E | V | W | A | E | V | S | E |
| Template Known Secondary structure |   |
 |  |  |  | T | S |
| G | G | . | . | G |
|
|  |  |  |  |  | T | T | T | T | T | T |
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| S | S |
| S | S | S |
|
| S |
|  |  |  |  |  |  |  | T |
|
|
|
|
|  |  |  |  | T | T | S |
|  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
381 | . | . | . | . | . | . | . | . | |
|
390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | |
. | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . |
|   |
|   |   |
468 | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | L | Y | Q | L | M | R | L | C | W | K | E | R | P | E | D | R | P | T | F | D | Y | L | R | S |
| Query Conservation |   |
  |
|   |   |
|
|   |   |
|   |   |   |
|
|   |   |
|
|
|   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |
|
|   |   |   |
|   |   |
|
|   |   |
|   |
|   |   |
|
|
|   |
| Template Sequence |   |
K | A | L | D | L | V | K | K | L | L | V | V | D | P | K | A | R | F | T | T | E | E | A | L | R |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | S |
| S | S | T | T | T | S |
|
|  |  |  |  |  | T |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
458 | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . |
|   |