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Job DescriptionP06239
Confidence100.00%DateWed May 9 17:41:23 BST 2012
Rank5Aligned Residues431
% Identity71%Templatec2c0iA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983
Resolution2.30 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   65....70.........80.........90.........100.........110.........120.........130.........140....
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Query Sequence  LVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFVAKANSLEPEPWFFKNLSRKDAERQLLAP
Query Conservation     
 
        

    

   
      
        
  
  
   
     
    

 
 
 
 


  
   
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Template Conservation     
          

    

   

     

          
 

 
 
     
    

 
 


  

  
   
Template Sequence  IVVALYDYEAIHHEDLSFQKGDQMVVLEESGEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAP
Template Known Secondary structure  SS
B


SSSB

B
TT
TTTTT

GGGTTSGGGSTTTT

TST
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   61........70.........80.........90.........100.........110.........120.........130.........140
 
   145....150.........160.........170.........180.........190.........200.........210.........220....
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Query Sequence  GNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPC
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Template Sequence  GNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPC
Template Known Secondary structure  T

TT

SSSTT
TTTB

STT
SSTTSSSTTSS
SS
SS


SB
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   141........150.........160.........170.........180.........190.........200.........210.........220
 
   225....230.........240.........250.........260.........270.........280.........290.........300....
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Query Sequence  QTQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLY
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Template Sequence  MSSKPQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVEAFLAEANVMKTLQHDKLVKLH
Template Known Secondary structure 









TT
SB

GGGTTTTT


SS
T


TTB

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   221........230.........240.........250.........260.........270.........280.........290.........300
 
   305....310.........320.........330.........340.........350.........360.........370.........380....
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Query Sequence  AVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFG
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Template Conservation 
        

 
    
 
   
                   
   
        

  
   


       
  


Template Sequence  AVVTKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFG
Template Known Secondary structure 
SSS


TT
BSTTGGG

TT


S

SGGG
TT



TT
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   301........310.........320.........330.........340.........350.........360.........370.........380
 
   385....390.........400.........410.........420.........430.........440.........450.........460....
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Query Sequence  LARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDN
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Template Sequence  LAR. . . . . . . . . . . . . VIPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPEN
Template Known Secondary structure  GGG.............T

GGGS




TTT

SSTT

TT





TT
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   381.. ......390.........400.........410.........420.........430.........440.......
 
   465....470.........480.........490.........500........
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Query Sequence  CPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTATEGQYQPQ
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Template Sequence  CPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQEEIP
Template Known Secondary structure 

T
SSGGGS

TTTS
GGG




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   461........470.........480.........490.........500....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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