Emaill.a.kelley@imperial.ac.uk
DescriptionA1IGU5
DateThu Apr 26 09:49:45 BST 2012
Unique Job IDf8052f883022ad14

Detailed template information 

#Template Alignment Coverage3D Model Confidence% i.d. Template Information
1c2dx1A_



100.0 23 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crystal structure of rhogef protein asef
2c3ky9B_



100.0 26 PDB header:apoptosis
Chain: B: PDB Molecule:proto-oncogene vav;
PDBTitle: autoinhibited vav1
3c2vrwB_



100.0 26 PDB header:signaling protein
Chain: B: PDB Molecule:proto-oncogene vav;
PDBTitle: critical structural role for the ph and c1 domains of the2 vav1 exchange factor
4c3odoA_



100.0 19 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 1;
PDBTitle: crystal structure of the dh/ph domains of p115-rhogef
5c3ksyA_



100.0 22 PDB header:signaling protein
Chain: A: PDB Molecule:son of sevenless homolog 1;
PDBTitle: crystal structure of the histone domain, dh-ph unit, and2 catalytic unit of the ras activator son of sevenless (sos)
6c1xcgA_



100.0 23 PDB header:signaling protein activator/signaling pr
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 11;
PDBTitle: crystal structure of human rhoa in complex with dh/ph2 fragment of pdzrhogef
7c1foeA_



100.0 25 PDB header:signaling protein, immune system/signali
Chain: A: PDB Molecule:t-lymphoma invasion and metastasis inducing
PDBTitle: crystal structure of rac1 in complex with the guanine2 nucleotide exchange region of tiam1
8d1xcga1



100.0 23 Fold:DBL homology domain (DH-domain)
Superfamily:DBL homology domain (DH-domain)
Family:DBL homology domain (DH-domain)
9c2dfkA_



100.0 24 PDB header:cell cycle
Chain: A: PDB Molecule:collybistin ii;
PDBTitle: crystal structure of the cdc42-collybistin ii complex
10c1x86A_



100.0 19 PDB header:signaling protein/membrane protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 12;
PDBTitle: crystal structure of the dh/ph domains of leukemia-associated rhogef2 in complex with rhoa
11c3t06E_



100.0 22 PDB header:signaling protein
Chain: E: PDB Molecule:rho guanine nucleotide exchange factor 11;
PDBTitle: crystal structure of the dh/ph fragment of pdzrhogef with n-terminal2 regulatory elements in complex with human rhoa
12c3bjiA_



100.0 25 PDB header:signaling protein
Chain: A: PDB Molecule:proto-oncogene vav;
PDBTitle: structural basis of promiscuous guanine nucleotide exchange2 by the t-cell essential vav1
13d2dfka1



100.0 25 Fold:DBL homology domain (DH-domain)
Superfamily:DBL homology domain (DH-domain)
Family:DBL homology domain (DH-domain)
14d1txda1



100.0 19 Fold:DBL homology domain (DH-domain)
Superfamily:DBL homology domain (DH-domain)
Family:DBL homology domain (DH-domain)
15c2z0qA_



100.0 24 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 3;
PDBTitle: crystal structure of dh-ph domain of rhogef3(xpln)
16c1xdvB_



100.0 21 PDB header:signaling protein
Chain: B: PDB Molecule:son of sevenless protein homolog 1;
PDBTitle: experimentally phased structure of human the son of2 sevenless protein at 4.1 ang.
17c1ki1B_



100.0 24 PDB header:signaling protein
Chain: B: PDB Molecule:intersectin long form;
PDBTitle: guanine nucleotide exchange region of intersectin in2 complex with cdc42
18d1foea1



100.0 26 Fold:DBL homology domain (DH-domain)
Superfamily:DBL homology domain (DH-domain)
Family:DBL homology domain (DH-domain)
19d1dbha1



100.0 21 Fold:DBL homology domain (DH-domain)
Superfamily:DBL homology domain (DH-domain)
Family:DBL homology domain (DH-domain)
20d1by1a_



100.0 22 Fold:DBL homology domain (DH-domain)
Superfamily:DBL homology domain (DH-domain)
Family:DBL homology domain (DH-domain)
21c3eo2A_



not modelled 100.0 25 PDB header:splicing
Chain: A: PDB Molecule:neuroepithelial cell-transforming gene 1 protein;
PDBTitle: crystal structure of the rhogef domain of human neuroepithelial cell-2 transforming gene 1 protein
22c1lb1C_



not modelled 100.0 26 PDB header:signaling protein
Chain: C: PDB Molecule:guanine nucleotide exchange factor dbs;
PDBTitle: crystal structure of the dbl and pleckstrin homology2 domains of dbs in complex with rhoa
23c2rgnB_



not modelled 100.0 21 PDB header:signaling protein complex
Chain: B: PDB Molecule:rhoa/rac/cdc42 exchange factor;
PDBTitle: crystal structure of p63rhogef complex with galpha-q and rhoa
24d1ki1b1



not modelled 100.0 22 Fold:DBL homology domain (DH-domain)
Superfamily:DBL homology domain (DH-domain)
Family:DBL homology domain (DH-domain)
25c3mpxA_



not modelled 100.0 24 PDB header:lipid binding protein
Chain: A: PDB Molecule:fyve, rhogef and ph domain-containing protein 5;
PDBTitle: crystal structure of the dh and ph-1 domains of human fgd5
26d1f5xa_



not modelled 100.0 23 Fold:DBL homology domain (DH-domain)
Superfamily:DBL homology domain (DH-domain)
Family:DBL homology domain (DH-domain)
27c3odwB_



not modelled 100.0 20 PDB header:signaling protein
Chain: B: PDB Molecule:rho guanine nucleotide exchange factor 1;
PDBTitle: crystal structure of the linker-dh/ph domains of p115-rhogef
28c1dbhA_



not modelled 100.0 19 PDB header:gene regulation
Chain: A: PDB Molecule:protein (human sos 1);
PDBTitle: dbl and pleckstrin homology domains from hsos1
29c3odxA_



not modelled 100.0 20 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 1;
PDBTitle: crystal structure of an n-terminally truncated linker-dh/ph domains of2 p115-rhogef
30d1kz7a1



not modelled 100.0 26 Fold:DBL homology domain (DH-domain)
Superfamily:DBL homology domain (DH-domain)
Family:DBL homology domain (DH-domain)
31c1ntyA_



not modelled 100.0 19 PDB header:signaling protein
Chain: A: PDB Molecule:triple functional domain protein;
PDBTitle: crystal structure of the first dh/ph domain of trio to 1.7 a
32d1ntya1



not modelled 100.0 19 Fold:DBL homology domain (DH-domain)
Superfamily:DBL homology domain (DH-domain)
Family:DBL homology domain (DH-domain)
33c3gf9A_



not modelled 100.0 27 PDB header:endocytosis
Chain: A: PDB Molecule:intersectin 2;
PDBTitle: crystal structure of human intersectin 2 rhogef domain
34c1griA_



99.9 18 PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2
35c2eyzA_



99.9 19 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii
36c2l3sA_



99.9 17 PDB header:structural protein
Chain: A: PDB Molecule:autoinhibited crk protein;
PDBTitle: structure of the autoinhibited crk
37c1mv3A_



99.9 14 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:myc box dependent interacting protein 1;
PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc
38c1ng2A_



99.9 22 PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosolic factor 1;
PDBTitle: structure of autoinhibited p47phox
39c1ov3A_



99.9 23 PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosol factor 1;
PDBTitle: structure of the p22phox-p47phox complex
40c2ficA_



99.8 15 PDB header:endocytosis/exocytosis, membrane protein
Chain: A: PDB Molecule:bridging integrator 1;
PDBTitle: the crystal structure of the bar domain from human bin1/amphiphysin ii2 and its implications for molecular recognition
41d1urua_



99.7 20 Fold:BAR/IMD domain-like
Superfamily:BAR/IMD domain-like
Family:BAR domain
42c1uruA_



99.7 20 PDB header:endocytosis
Chain: A: PDB Molecule:amphiphysin;
PDBTitle: amphiphysin bar domain from drosophila
43c3sogA_



99.7 16 PDB header:structural protein
Chain: A: PDB Molecule:amphiphysin;
PDBTitle: crystal structure of the bar domain of human amphiphysin, isoform 1
44c2e5kA_



not modelled 99.7 14 PDB header:protein binding
Chain: A: PDB Molecule:suppressor of t-cell receptor signaling 1;
PDBTitle: solution structure of sh3 domain in suppressor of t-cell2 receptor signaling 1
45d1ng2a2



not modelled 99.7 19 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
46d1udla_



not modelled 99.7 33 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
47d1uhca_



not modelled 99.7 38 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
48c2rqrA_



not modelled 99.7 18 PDB header:protein binding
Chain: A: PDB Molecule:engulfment and cell motility protein 1, linker, dedicator
PDBTitle: the solution structure of human dock2 sh3 domain - elmo1 peptide2 chimera complex
49c2dlpA_



not modelled 99.7 19 PDB header:structural protein
Chain: A: PDB Molecule:kiaa1783 protein;
PDBTitle: solution structure of the sh3 domain of human kiaa17832 protein
50c2eyyA_



not modelled 99.7 13 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i
51c2ed0A_



not modelled 99.6 17 PDB header:signaling protein
Chain: A: PDB Molecule:abl interactor 2;
PDBTitle: solution structure of the sh3 domain of abl interactor 22 (abelson interactor 2)
52c2jxbA_



not modelled 99.6 20 PDB header:signaling protein complex
Chain: A: PDB Molecule:t-cell surface glycoprotein cd3 epsilon chain,
PDBTitle: structure of cd3epsilon-nck2 first sh3 domain complex
53d1ug1a_



not modelled 99.6 27 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
54c3nmzD_



not modelled 99.6 18 PDB header:cell adhesion/cell cycle
Chain: D: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crytal structure of apc complexed with asef
55c2cudA_



not modelled 99.6 13 PDB header:signaling protein
Chain: A: PDB Molecule:src-like-adapter;
PDBTitle: solution structure of the sh3 domain of the human src-like2 adopter protein (slap)
56d1ov3a2



not modelled 99.6 20 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
57c1x6gA_



not modelled 99.6 25 PDB header:signaling protein
Chain: A: PDB Molecule:megakaryocyte-associated tyrosine-protein kinase;
PDBTitle: solution structures of the sh3 domain of human2 megakaryocyte-associated tyrosine-protein kinase.
58c2dl7A_



not modelled 99.6 22 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:kiaa0769 protein;
PDBTitle: solution structure of the second sh3 domain of human2 kiaa0769 protein
59c2csqA_



not modelled 99.6 12 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:rim binding protein 2;
PDBTitle: solution structure of the second sh3 domain of human rim-2 binding protein 2
60c2oi3A_



not modelled 99.6 25 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: nmr structure analysis of the hematopoetic cell kinase sh32 domain complexed with an artificial high affinity ligand3 (pd1)
61d1ycsb2



not modelled 99.6 24 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
62c2nwmA_



not modelled 99.6 27 PDB header:cell adhesion
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the first sh3 domain of human vinexin2 and its interaction with the peptides from vinculin
63d1i1ja_



not modelled 99.6 17 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
64c2yt6A_



not modelled 99.6 20 PDB header:cell cycle
Chain: A: PDB Molecule:adult male urinary bladder cdna, riken full-
PDBTitle: solution structure of the sh3_1 domain of yamaguchi sarcoma2 viral (v-yes) oncogene homolog 1
65c2egeA_



not modelled 99.6 25 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein kiaa1666;
PDBTitle: solution structure of the third sh3 domain from human2 kiaa1666 protein
66d2v1ra1



not modelled 99.6 30 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
67c2yupA_



not modelled 99.6 18 PDB header:cell adhesion
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the second sh3 domain of human vinexin
68c1x2qA_



not modelled 99.6 19 PDB header:signaling protein
Chain: A: PDB Molecule:signal transducing adapter molecule 2;
PDBTitle: solution structure of the sh3 domain of the signal2 transducing adaptor molecule 2
69d1gbra_



not modelled 99.6 24 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
70c2df6A_



not modelled 99.6 22 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 7;
PDBTitle: crystal structure of the sh3 domain of betapix in complex2 with a high affinity peptide from pak2
71c2dnuA_



not modelled 99.6 17 PDB header:structural genomics, structural protein
Chain: A: PDB Molecule:sh3 multiple domains 1;
PDBTitle: solution structure of rsgi ruh-061, a sh3 domain from human
72c1x43A_



not modelled 99.6 21 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:sh3 domain grb2-like protein b1;
PDBTitle: solution structure of the sh3 domain of endophilin b12 (sh3g1b1)
73c2dl4A_



not modelled 99.6 27 PDB header:signaling protein
Chain: A: PDB Molecule:protein stac;
PDBTitle: solution structure of the first sh3 domain of stac protein
74c2ysqA_



not modelled 99.6 19 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 9;
PDBTitle: solution structure of the sh3 domain from rho guanine2 nucleotide exchange factor 9
75c2epdA_



not modelled 99.6 21 PDB header:protein binding
Chain: A: PDB Molecule:rho gtpase-activating protein 4;
PDBTitle: solution structure of sh3 domain in rho-gtpase-activating2 protein 4
76c2kbtA_



not modelled 99.6 30 PDB header:signaling protein
Chain: A: PDB Molecule:chimera of proto-oncogene vav, linker,
PDBTitle: attachment of an nmr-invisible solubility enhancement tag2 (inset) using a sortase-mediated protein ligation method
77c2xmfA_



not modelled 99.6 20 PDB header:motor protein
Chain: A: PDB Molecule:myosin 1e sh3;
PDBTitle: myosin 1e sh3
78c1zlmA_



not modelled 99.6 25 PDB header:signaling protein
Chain: A: PDB Molecule:osteoclast stimulating factor 1;
PDBTitle: crystal structure of the sh3 domain of human osteoclast2 stimulating factor
79c2cubA_



not modelled 99.6 19 PDB header:signaling protein
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck1
80d1gcqa_



not modelled 99.6 22 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
81c1x2pA_



not modelled 99.6 22 PDB header:transferase
Chain: A: PDB Molecule:protein arginine n-methyltransferase 2;
PDBTitle: solution structure of the sh3 domain of the protein2 arginine n-methyltransferase 2
82d1u5sa1



not modelled 99.6 23 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
83c3qwxX_



not modelled 99.6 20 PDB header:signaling protein
Chain: X: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2 1-174
84c2yunA_



not modelled 99.6 31 PDB header:protein transport
Chain: A: PDB Molecule:nostrin;
PDBTitle: solution structure of the sh3 domain of human nostrin
85c2yuoA_



not modelled 99.6 22 PDB header:signaling protein
Chain: A: PDB Molecule:run and tbc1 domain containing 3;
PDBTitle: solution structure of the sh3 domain of mouse run and tbc12 domain containing 3
86c2l0aA_



not modelled 99.6 29 PDB header:signaling protein
Chain: A: PDB Molecule:signal transducing adapter molecule 1;
PDBTitle: solution nmr structure of signal transducing adapter molecule 1 stam-12 from homo sapiens, northeast structural genomics consortium target3 hr4479e
87c1wyxA_



not modelled 99.6 33 PDB header:cell adhesion
Chain: A: PDB Molecule:crk-associated substrate;
PDBTitle: the crystal structure of the p130cas sh3 domain at 1.1 a2 resolution
88c2ekhA_



not modelled 99.6 21 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a;
PDBTitle: solution structures of the sh3 domain of human kiaa0418
89c2djqA_



not modelled 99.6 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:sh3 domain containing ring finger 2;
PDBTitle: the solution structure of the first sh3 domain of mouse sh32 domain containing ring finger 2
90d1oota_



not modelled 99.6 27 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
91c2kymA_



not modelled 99.6 22 PDB header:signaling protein
Chain: A: PDB Molecule:bud emergence protein 1;
PDBTitle: solution structure of the bem1p sh3-ci domain from l.elongisporus in2 complex with ste20p peptide
92d1wlpb2



not modelled 99.6 20 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
93d1nega_



not modelled 99.6 32 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
94c1negA_



not modelled 99.6 32 PDB header:structural protein
Chain: A: PDB Molecule:spectrin alpha chain, brain;
PDBTitle: crystal structure analysis of n-and c-terminal labeled sh3-2 domain of alpha-chicken spectrin
95d1k4us_



not modelled 99.6 24 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
96c2dvjA_



not modelled 99.6 13 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog,
PDBTitle: phosphorylated crk-ii
97c2dmoA_



not modelled 99.6 28 PDB header:signaling protein
Chain: A: PDB Molecule:neutrophil cytosol factor 2;
PDBTitle: refined solution structure of the 1st sh3 domain from human2 neutrophil cytosol factor 2 (ncf-2)
98c2dilA_



not modelled 99.6 29 PDB header:cell adhesion
Chain: A: PDB Molecule:proline-serine-threonine phosphatase-interacting
PDBTitle: solution structure of the sh3 domain of the human proline-2 serine-threonine phosphatase-interacting protein 1
99c3qwyA_



not modelled 99.6 20 PDB header:signaling protein
Chain: A: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2
100d1gria2



not modelled 99.6 21 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
101d1u06a1



not modelled 99.6 33 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
102d1pwta_



not modelled 99.6 31 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
103c2pqhA_



not modelled 99.6 30 PDB header:structural protein
Chain: A: PDB Molecule:spectrin alpha chain, brain;
PDBTitle: structure of sh3 chimera with a type ii ligand linked to the chain c-2 terminal
104d1utia_



not modelled 99.6 25 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
105c2dbkA_



not modelled 99.6 16 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structures of the sh3 domain of human crk-like2 protein
106d1uuea_



not modelled 99.6 33 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
107d1oeba_



not modelled 99.6 24 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
108c2egaA_



not modelled 99.6 24 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a;
PDBTitle: solution structure of the first sh3 domain from human2 kiaa0418 protein
109d1jqqa_



not modelled 99.6 23 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
110c2o2oA_



not modelled 99.6 16 PDB header:protein binding
Chain: A: PDB Molecule:sh3-domain kinase-binding protein 1;
PDBTitle: solution structure of domain b from human cin85 protein
111d1uffa_



not modelled 99.6 24 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
112d1bb9a_



not modelled 99.6 24 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
113c1bb9A_



not modelled 99.6 24 PDB header:transferase
Chain: A: PDB Molecule:amphiphysin 2;
PDBTitle: crystal structure of the sh3 domain from rat amphiphysin 2
114c2csiA_



not modelled 99.6 31 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:rim binding protein 2;
PDBTitle: solution structure of the third sh3 domain of human rim-2 binding protein 2
115c2bz8B_



not modelled 99.6 24 PDB header:sh3 domain
Chain: B: PDB Molecule:sh3-domain kinase binding protein 1;
PDBTitle: n-terminal sh3 domain of cin85 bound to cbl-b peptide
116c2eyxA_



not modelled 99.6 17 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: c-terminal sh3 domain of ct10-regulated kinase
117c1zx6A_



not modelled 99.6 31 PDB header:protein binding
Chain: A: PDB Molecule:ypr154wp;
PDBTitle: high-resolution crystal structure of yeast pin3 sh3 domain
118c2ebpA_



not modelled 99.6 13 PDB header:cell adhesion
Chain: A: PDB Molecule:sam and sh3 domain-containing protein 1;
PDBTitle: solution structure of the sh3 domain from human sam and sh32 domain containing protein 1
119c2rf0D_



not modelled 99.6 25 PDB header:transferase
Chain: D: PDB Molecule:mitogen-activated protein kinase kinase kinase 10;
PDBTitle: crystal structure of human mixed lineage kinase map3k10 sh3 domain
120c2fpeB_



not modelled 99.6 22 PDB header:signaling protein
Chain: B: PDB Molecule:c-jun-amino-terminal kinase interacting protein
PDBTitle: conserved dimerization of the ib1 src-homology 3 domain