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Job DescriptionP51813
Confidence100.00%DateFri May 25 10:09:19 BST 2012
Rank98Aligned Residues332
% Identity23%Templatec3o96A_
PDB info PDB header:transferaseChain: A: PDB Molecule:rac-alpha serine/threonine-protein kinase; PDBTitle: crystal structure of human akt1 with an allosteric inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   2.......10.........20.........30.........40.........50.........60.........70.........80.
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Query Sequence  DTKSILEELLLKRSQQKKKMSPNNYKERLFVLTKTNLSYYEYDKMKRGSRKGSIEIKKIRCVEKVNLEEQTPVERQYPFQ
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Template Sequence  DVAIVKEGWLHKRGE. . . . . YIKTWRPRYFLLKNDGTFIGYKERPQ. . DVEAPLNNFSVAQCQLM. . . . KTERPRPNTFI
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S.....SS

TTSBSS

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GGGB
TT



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SSSSS
B
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   3......10....... ..20.........30.........40... ......50.........60 .........70.
 
   82..... ..90.........100.........110.........120.........130.........140.........150.........160
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Query Sequence  IVYKDG. LLYVYASNEESRSQWLKALQKEIRGNPHLLVKYHSGFFVDGKFLCCQQSCKAAPGCTLWEAYANLHTAVNEEK
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Template Sequence  IRCLQWTTVIERTFTPEEREEWTTAIQTVADGLKKQVTM. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  TT

TTGGGTT


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   75....80.........90.........100.........110...
 
   161........170.........180.........190.........200.........210.........220.........230.........240
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Query Sequence  HRVPTFPDRVLKIPRAVPVLKMDAPSSSTTLAQYDNESKKNYGSQPPSSSTSLAQYDSNSKKIYGSQPNFNMQYIPREDF
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   241........250.........260.........270.........280.........290.........300.........310.........320
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Query Sequence  PDWWQVRKLKSSSSSEDVASSNQKERNVNHTTSKISWEFPESSSSEEEENLDDYDWFAGNISRSQSEQLLRQKGKEGAFM
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   321........330.........340.........350.........360.........370.........380.........390.........400
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Query Sequence  VRNSSQVGMYTVSLFSKAVNDKKGTVKHYHVHTNAENKLYLAENYCFDSIPKLIHYHQHNSAGMITRLRHPVSTKANKVP
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   401........410.........420.........430....... ..440.........450.........460.........470.........
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Query Sequence  DSVSLGNGIWELKREEITLLKELGSGQFGVVQLGKWK. GQYDVAVKMIKEGSMSEDEFFQEAQTMMKLSHPKLVKFYGVC
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Template Sequence  . . . . . . . . . . . . . . NEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILK. . . . . . KEVIVANRVLQNSRHPFLTALKYSF
Template Known Secondary structure  ..............TSTTTTT

......GGGS



GGGTS

TTB

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   148.150.........160.........170.........180.. .......190.........200.......
 
   480.........490.........500.........510.........520.........530 .........540.........550........
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Query Sequence  SKEYPIYIVTEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEGMAFLESH. QFIHRDLAARNCLVDRDLCVKVSDFGMT
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Template Sequence  QTHDRLCFVMEYANGGELFFHLSRE. RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLC
Template Known Secondary structure 
SS

SS
B.SS

TS







GGG
TTS




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   218.220.........230.........240.. .......250.........260.........270.........280.........290......
 
   559560.........570.........580.........590.........600.........610.........620.........630........
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Query Sequence  RYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQVVLKVSQGHRLYRPHLAS
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Template Sequence  KEPE. . . . . . . . . . . . . . . YLAPEVLEDNDYGRAVDWWGLGVVMYEMMC. GRLPFYNQDHEKLFELILMEE. IRFPRTLG
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   297..300 .........310.........320.........330 .........340.........350. ........
 
   639640.........650...... ...660...
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Query Sequence  DTIYQIMYSCWHELPEKR. . . . . PTFQQLL
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Template Sequence  PEAKSLLSGLLKKDPKQRLGGGSEDAKEIM
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SSTTTSTT
STTT
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   374.....380.........390.........400...
 
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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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