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Job DescriptionP51813
Confidence100.00%DateFri May 25 10:09:19 BST 2012
Rank180Aligned Residues251
% Identity24%Templatec3mtfB_
PDB info PDB header:transferaseChain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor
Resolution2.15 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   415....420.........430.........440.........450.........460.........470........ .480.........490
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Query Sequence  EEITLLKELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSEDEFFQEAQTMMKLSHPKLVKFYGV. . . . CSKEYPIYIVTE
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Template Sequence  RDITLLECVGKGRYGEVWRGSW. QGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITH
Template Known Secondary structure  TTTT.TT
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   206...210.........220....... ..230.........240.........250.........260.........270.........280....
 
   491........500.........510.........520.........530.. .......540.........550.........560..
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Query Sequence  YISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEGMAFLESHQF. . . . . . . . IHRDLAARNCLVDRDLCVKVSDFGMTRYVL
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Template Sequence  YHEMGSLYDYLQLTT. . LDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHS
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B

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STT
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   285....290......... 300.........310.........320.........330.........340.........350.........360..
 
   563......570.........580........ .590.........600.........610........
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Query Sequence  . . . DDQYVSSVGTKFPVKWSAPEVFHYFK. . . . . . YSSKSDVWAFGILMWEVFSLGKQPYDLYDN. . . . . . . . . . . . . . .
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Template Sequence  QSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVAR. RMVSNGIVEDYKPPFYDVVPNDPSF
Template Known Secondary structure  TTTT








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   363......370.........380.........390.........400.........410...... ...420.........430.........440.
 
   619620.........630...... ...640.........650.........660.........
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Query Sequence  SQVVLKVSQGHRLYRPHL. . . . . . ASDTIYQIMYSCWHELPEKRPTFQQLLSSIEPL
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Template Sequence  EDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKI
Template Known Secondary structure  TTS






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   442.......450.........460.........470.........480.........490........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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