Job Description P51813 Confidence 100.00% Date Fri May 25 10:09:19 BST 2012 Rank 89 Aligned Residues 257 % Identity 32% Template c3lxnA_ PDB info PDB header:transferase Chain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2; PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6 Resolution 2.50 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		411	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.						.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.			.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.
Predicted Secondary structure																													.	.	.	.	.																		.	.
Query SS confidence																													.	.	.	.	.																		.	.
Query Sequence		E	L	K	R	E	E	I	T	L	L	K	E	L	G	S	G	Q	F	G	V	V	Q	L	G	K	W	K	.	.	.	.	.	G	Q	Y	D	V	A	V	K	M	I	K	E	G	S	M	S	E	.	.	D	E	F	F	Q	E	A	Q	T	M	M	K	L	S	H	P	K	L	V	K	F	Y	G	V	C	S	K	E	Y
Query Conservation																													.	.	.	.	.																		.	.
Alig confidence																													.	.	.	.	.																		.	.
Template Conservation
Template Sequence		V	F	H	K	R	Y	L	K	K	I	R	D	L	G	E	G	H	F	G	K	V	S	L	Y	C	Y	D	P	T	N	D	G	T	G	E	M	V	A	V	K	A	L	K	A	D	A	G	P	Q	H	R	S	G	W	K	Q	E	I	D	I	L	R	T	L	Y	H	E	H	I	I	K	Y	K	G	C	C	E	D	A	G
Template Known Secondary structure					G	G	G											S	S										T	T	S	S	S												S	S																						T	T	B										T	T
Template Predicted Secondary structure
Template SS confidence
		891	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970
				484	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.
Predicted Secondary structure		.	.
Query SS confidence		.	.
Query Sequence		.	.	P	I	Y	I	V	T	E	Y	I	S	N	G	C	L	L	N	Y	L	R	S	H	G	K	G	L	E	P	S	Q	L	L	E	M	C	Y	D	V	C	E	G	M	A	F	L	E	S	H	Q	F	I	H	R	D	L	A	A	R	N	C	L	V	D	R	D	L	C	V	K	V	S	D	F	G	M	T	R	Y	V
Query Conservation		.	.
Alig confidence		.	.																			.	.
Template Conservation																						.	.
Template Sequence		A	A	S	L	Q	L	V	M	E	Y	V	P	L	G	S	L	R	D	Y	L	.	.	P	R	H	S	I	G	L	A	Q	L	L	L	F	A	Q	Q	I	C	E	G	M	A	Y	L	H	A	Q	H	Y	I	H	R	D	L	A	A	R	N	V	L	L	D	N	D	R	L	V	K	I	G	D	F	G	L	A	K	A	V
Template Known Secondary structure		T	T										T	T		B					G	.	.	G	G	S																								T	T				S			S	G	G	G						T	T								T	T
Template Predicted Secondary structure																						.	.
Template SS confidence
		971	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990			.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.
		562	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.																.	.	.	.	.	620	.	.	.	.	.	.
Predicted Secondary structure																																																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		L	D	D	Q	Y	V	S	S	V	G	T	K	F	P	V	K	W	S	A	P	E	V	F	H	Y	F	K	Y	S	S	K	S	D	V	W	A	F	G	I	L	M	W	E	V	F	S	L	G	K	Q	P	Y	D	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	L	Y	D	N	S	Q	V	V	L	K	V	S
Query Conservation																																																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence														.	.																																	.							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation														.	.																																	.
Template Sequence		P	E	G	H	E	Y	R	V	G	D	S	P	.	.	V	F	W	Y	A	P	E	C	L	K	E	Y	K	F	Y	Y	A	S	D	V	W	S	F	G	V	T	L	Y	E	L	L	T	.	H	C	D	S	S	Q	S	P	P	T	K	F	L	E	L	I	G	I	A	Q	G	Q	M	T	V	L	R	L	T	E	L	L	E
Template Known Secondary structure			T	T				B						.	.	G	G	G								S		B																			T	.	T	T		G	G	G	S											S	T	T	G	G	G
Template Predicted Secondary structure														.	.																																	.
Template SS confidence
		1049	1050	.	.	.	.	.	.	.	.	.	1060			.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.		.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.
		627	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	G	H	R	L	Y	R	P	H	L	A	S	D	T	I	Y	Q	I	M	Y	S	C	W	H	E	L	P	E	K	R	P	T	F	Q	Q	L	L	S	S	I	E	P	L	R	E	K
Query Conservation
Alig confidence
Template Conservation
Template Sequence		R	G	E	R	L	P	R	P	D	K	C	P	A	E	V	Y	H	L	M	K	N	C	W	E	T	E	A	S	F	R	P	T	F	E	N	L	I	P	I	L	K	T	V	H	E	K
Template Known Secondary structure		T	T							T	T													T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions