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Job DescriptionP51813
Confidence100.00%DateFri May 25 10:09:19 BST 2012
Rank40Aligned Residues257
% Identity33%Templatec3lxkA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase jak3; PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6
Resolution2.00 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   412.......420.........430...... ...440.........450. ........460.........470.........480. ..
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Query Sequence  LKREEITLLKELGSGQFGVVQLGKW. . . . . KGQYDVAVKMIKEGS. MSEDEFFQEAQTMMKLSHPKLVKFYGVCSK. . EY
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Template Sequence  FEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQ
Template Known Secondary structure 

GGGTT
TTSSS
SSS

T


TTB

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   817..820.........830.........840.........850.........860.........870.........880.........890......
 
   484.....490.........500.........510.........520.........530.........540.........550.........560...
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Query Sequence  PIYIVTEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLD
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Template Sequence  SLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPL
Template Known Secondary structure 

TT
BGGG

TT
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SGGGTT


TT


T
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   897..900.........910.........920.........930.........940.........950.........960.........970......
 
   564.....570.........580.........590.........600.........610..... ....620.........630.
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Query Sequence  . . DQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDL. . . . . . . . . . YDNSQVVLKVSQGHRL
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Template Sequence  DKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFT. YCDKSCSPSAEFLRMMVPALSRLLELLEEGQRL
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SS


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   977..980.........990.........1000.........1010.........1020.. .......1030.........1040.........1050.....
 
   632.......640.........650.........660.........
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Query Sequence  YRPHLASDTIYQIMYSCWHELPEKRPTFQQLLSSIEPL
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Template Sequence  PAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDML
Template Known Secondary structure 


TT

T
SSGGGS


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   1061........1070.........1080.........1090........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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