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Job DescriptionP51813
Confidence100.00%DateFri May 25 10:09:19 BST 2012
Rank92Aligned Residues243
% Identity63%Templatec3k54A_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases.
Resolution1.94 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   407..410.........420.........430.........440.........450.........460.........470.........480......
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Query Sequence  NGIWELKREEITLLKELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKEYPIY
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Template Sequence  YGSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKE. . . . . . . FIEEAKVMMNLSHEKLVQLYGVCTKQRPIF
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GGGB

GGGSTTSS
TTT


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TT


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   392.......400.........410.........420.........430.... .....440.........450.........460....
 
   487..490.........500.........510.........520.........530.........540.........550.........560......
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Query Sequence  IVTEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLDDQY
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Template Sequence  IITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGFPVR. . . . . .
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TT
GGG


TT


S

SGGG
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GG......
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   472.......480.........490.........500.........510.........520.........530.........540.....
 
   567..570.........580.........590.........600.........610.........620.........630.........640......
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Query Sequence  VSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQVVLKVSQGHRLYRPHLASDTIYQIMY
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Template Sequence  . . . . . . . . . . . WSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMY
Template Known Secondary structure  ...........G





TTS

TTTTS
TT





TTS
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   563......570.........580.........590.........600.........610.........620.........630.
 
   647..650.........660.........670...
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Query Sequence  SCWHELPEKRPTFQQLLSSIEPLREKD
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Template Sequence  SCWHEKADERPTFKILLSNILDVMDEE
Template Known Secondary structure  TT
SSGGGS


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   632.......640.........650........
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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