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Job DescriptionP51813
Confidence100.00%DateFri May 25 10:09:19 BST 2012
Rank79Aligned Residues250
% Identity33%Templatec3d4qA_
PDB info PDB header:transferaseChain: A: PDB Molecule:b-raf proto-oncogene serine/threonine-protein kinase; PDBTitle: pyrazole-based inhibitors of b-raf kinase
Resolution2.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   408.410.........420.........430.........440.........450..... ....460.........470.........480....
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Query Sequence  GIWELKREEITLLKELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSED. . . EFFQEAQTMMKLSHPKLVKFYGVCSKEYP
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Template Sequence  DDWEIPDGQITVGQRIGSGSFGTVYKGKWHGD. . VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYST. KPQ
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B

TT

TTSSS..

SSS

TT


TTB


.SSS
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   448.450.........460.........470......... 480.........490.........500.........510.........520. ...
 
   485....490.........500.........510.........520.........530.........540.........550.........560....
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Query Sequence  IYIVTEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLDD
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Template Sequence  LAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVL. . .
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SS
BTS




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S

SGGGTTT


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   525....530.........540.........550.........560.........570.........580.........590.........600.
 
   565....570.........580........ .590.........600.........610.........620.........630.. ....
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Query Sequence  QYVSSVGTKFPVKWSAPEVFHYFK. . . YSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQVVLKVSQGHRLY. . . . . RPHL
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Template Sequence  . . . . . . . . SGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMT. GQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSN
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TT

TT
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S.SS
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   614.....620.........630.........640.........650. ........660.........670.........680....
 
   637..640.........650.........660.........670..
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Query Sequence  ASDTIYQIMYSCWHELPEKRPTFQQLLSSIEPLREK
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Template Sequence  CPKAMKRLMAECLKKKRDERPLFPQILASIELLARS
Template Known Secondary structure  S
T
SSGGGS

T
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   685....690.........700.........710.........720
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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