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Job DescriptionP51813
Confidence100.00%DateFri May 25 10:09:19 BST 2012
Rank183Aligned Residues256
% Identity38%Templatec2yhvA_
PDB info PDB header:transferaseChain: A: PDB Molecule:alk tyrosine kinase receptor; PDBTitle: structure of l1196m mutant anaplastic lymphoma kinase
Resolution1.90 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   408.410.........420.........430.........440.........450..... ....460.........470.........480.....
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Query Sequence  GIWELKREEITLLKELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSED. . EFFQEAQTMMKLSHPKLVKFYGVCSKEYPI
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Template Sequence  DLKEVPRKNITL. . . IRGLAFGEVYEGQV. . PLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPR
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   1107..1110........ .1120.........1130.. .......1140.........1150.........1160.........1170.........1180.
 
   486...490.........500... ......510.........520.........530.........540......... 550......
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Query Sequence  YIVTEYISNGCLLNYLRS. . . . . . HGKGLEPSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLC. . . VKVSDFG
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Template Sequence  FILMELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFG
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   1193......1200.........1210.........1220.........1230.........1240.........1250.........1260.........1270..
 
   557..560.........570.........580.........590.........600.........610.........620.........630......
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Query Sequence  MTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQVVLKVSQGHRLYRPHL
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Template Sequence  M. . . . . ARDIYRGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKN
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   1273 ......1280.........1290.........1300.........1310.........1320.........1330.........1340.......
 
   637..640.........650.........660.........670...
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Query Sequence  ASDTIYQIMYSCWHELPEKRPTFQQLLSSIEPLREKD
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Template Sequence  CPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDP
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   1354.....1360.........1370.........1380.........1390
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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