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Job DescriptionP51813
Confidence100.00%DateFri May 25 10:09:19 BST 2012
Rank109Aligned Residues242
% Identity22%Templatec2r7bA_
PDB info PDB header:signaling protein, transferaseChain: A: PDB Molecule:phosphoinositide-dependent protein kinase 1; PDBTitle: crystal structure of the phosphoinositide-dependent kinase-2 1 (pdk-1)catalytic domain bound to a dibenzonaphthyridine3 inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   413......420.........430....... ..440........ .450.........460.........470.........480.......
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Query Sequence  KREEITLLKELGSGQFGVVQLGKWK. GQYDVAVKMIK. . . . EGSMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKEYPIYI
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Template Sequence  RPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYF
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   78.80.........90.........100.........110.........120.........130.........140.........150.......
 
   488.490.........500.........510.........520.........530.........540.........550.........560.......
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Query Sequence  VTEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLDDQYV
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Template Sequence  GLSYAKNGELLKYIRKI. GSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVL. . . . . .
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   158.160.........170.... .....180.........190.........200.........210.........220.........230
 
   568.570.........580.........590.........600.........610.........620.........630.........640.......
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Query Sequence  SSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQVVLKVSQGHRLYRPHLASDTIYQIMYS
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Template Sequence  . . . . FVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVA. GLPPFRAGNEYLIFQKIIKLE. YDFPEKFFPKARDLVEK
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   242.......250.........260.........270....... ..280.........290........ .300.........310.....
 
   648.650.........660.......
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Query Sequence  CWHELPEKRPTFQQLLSSIE
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Template Sequence  LLVLDATKRLGCEEMEGYGP
Template Known Secondary structure  TS
SSTTSSTTSGGGTT
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   316...320.........330.....
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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