Job Description P51813 Confidence 100.00% Date Fri May 25 10:09:19 BST 2012 Rank 5 Aligned Residues 428 % Identity 36% Template c1k9aB_ PDB info PDB header:transferase Chain: B: PDB Molecule:carboxyl-terminal src kinase; PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution Resolution 2.50 Å

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		203	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.			.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Predicted Secondary structure																																					.	.
Query SS confidence																																					.	.
Query Sequence		G	S	Q	P	P	S	S	S	T	S	L	A	Q	Y	D	S	N	S	K	K	I	Y	G	S	Q	P	N	F	N	M	Q	Y	I	P	R	.	.	E	D	F	P	D	W	W	Q	V	R	K	L	K	S	S	S	S	S	E	D	V	A	S	S	N	Q	K	E	R	N	V	N	H	T	T	S	K	I	S	W	E	F	P
Query Conservation																																					.	.
Alig confidence																																					.	.																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		Q	A	S	W	P	S	G	T	E	C	I	A	K	Y	N	F	H	G	T	A	E	Q	D	L	P	F	C	K	G	D	V	L	T	I	V	A	V	T	K	D	P	N	W	Y	K	A	K	N	K	V	G	R	E	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	I	I
Template Known Secondary structure			S				T	T						S	S		B			S	S	T	T	B			B		T	T										S	S	T	T							T	T	S			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		5	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.																									.	.	60
		281	.	.	.	.	.	.	.	.	290							.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.		.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.
Predicted Secondary structure												.	.	.	.	.	.																																			.
Query SS confidence												.	.	.	.	.	.																																			.
Query Sequence		E	S	S	S	S	E	E	E	E	N	.	.	.	.	.	.	L	D	D	Y	D	W	F	A	G	N	I	S	R	S	Q	S	E	Q	L	L	R	Q	K	G	K	E	G	A	F	M	V	R	N	S	.	S	Q	V	G	M	Y	T	V	S	L	F	S	K	A	V	N	D	K	K	G	T	V	K	H	Y	H	V	H	T
Query Conservation												.	.	.	.	.	.																																			.
Alig confidence												.	.	.	.	.	.																									.										.													.	.	.	.	.	.
Template Conservation																																										.																							.	.	.	.	.	.
Template Sequence		P	A	N	Y	V	Q	K	R	E	G	V	K	A	G	T	K	L	S	L	M	P	W	F	H	G	K	I	T	R	E	Q	A	E	R	L	L	Y	P	P	E	.	T	G	L	F	L	V	R	E	S	T	N	Y	P	G	D	Y	T	L	C	V	S	C	.	.	.	.	.	.	E	G	K	V	E	H	Y	R	I	M	Y
Template Known Secondary structure			G	G	G										S	S	S			S		T	T	B			S										T		S			.	T	T								S	S	S	T	T									.	.	.	.	.	.	T	T
Template Predicted Secondary structure																																										.																							.	.	.	.	.	.
Template SS confidence
		61	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100		.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.							.	.	.	.	.	.	.	130	.	.	.
		354	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		N	A	E	N	K	L	Y	L	A	E	N	Y	C	F	D	S	I	P	K	L	I	H	Y	H	Q	H	N	S	A	G	M	I	T	R	L	R	H	P	V	S	T	K	A	N	K	V	P	D	S	V	S	L	G	N	G	I	W	E	L	K	R	E	E	I	T	L	L	K	E	L	G	S	G	Q	F	G	V	V	Q	L
Query Conservation
Alig confidence		.																																																		.
Template Conservation		.																																																		.
Template Sequence		.	H	A	S	K	L	S	I	D	E	E	V	Y	F	E	N	L	M	Q	L	V	E	H	Y	T	T	D	A	D	G	L	C	T	R	L	I	K	P	K	V	M	E	G	T	V	A	A	Q	D	E	.	F	Y	R	S	G	W	A	L	N	M	K	E	L	K	L	L	Q	T	I	G	K	G	E	F	G	D	V	M	L
Template Known Secondary structure		.		T	T				S	S	S	S	S		B	S	S													T	T	S	S	S				S	B				S	S								.				T	T		B			G	G	G											T	T
Template Predicted Secondary structure		.																																																		.
Template SS confidence
			134	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.		.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.
		434	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.		.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.		.	.	.	.	.	.	510	.
Predicted Secondary structure																																																				.																					.
Query SS confidence																																																				.																					.
Query Sequence		G	K	W	K	G	Q	Y	D	V	A	V	K	M	I	K	E	G	S	M	S	E	D	E	F	F	Q	E	A	Q	T	M	M	K	L	S	H	P	K	L	V	K	F	Y	G	V	C	S	K	E	Y	.	P	I	Y	I	V	T	E	Y	I	S	N	G	C	L	L	N	Y	L	R	S	.	H	G	K	G	L	E	P	S
Query Conservation																																																				.																					.
Alig confidence						.																	.																													.																					.
Template Conservation						.																	.
Template Sequence		G	D	Y	R	.	G	N	K	V	A	V	K	C	I	K	N	D	A	T	A	Q	.	A	F	L	A	E	A	S	V	M	T	Q	L	R	H	S	N	L	V	Q	L	L	G	V	I	V	E	E	K	G	G	L	Y	I	V	T	E	Y	M	A	K	G	S	L	V	D	Y	L	R	S	R	G	R	S	V	L	G	G	D
Template Known Secondary structure					T	.	T									S	S		T	T	S		.										T	T				T	T	B										S	S	S										T	T		B										T	T	T
Template Predicted Secondary structure						.																	.
Template SS confidence
		212	.	.	.		.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.		.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.
		512	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	L	L	E	M	C	Y	D	V	C	E	G	M	A	F	L	E	S	H	Q	F	I	H	R	D	L	A	A	R	N	C	L	V	D	R	D	L	C	V	K	V	S	D	F	G	M	T	R	Y	V	L	D	D	Q	Y	V	S	S	V	G	T	K	F	P	V	K	W	S	A	P	E	V	F	H	Y	F	K	Y	S	S
Query Conservation
Alig confidence																																																		.	.	.	.	.	.	.	.	.	.
Template Conservation																																																		.	.	.	.	.	.	.	.	.	.
Template Sequence		C	L	L	K	F	S	L	D	V	C	E	A	M	E	Y	L	E	G	N	N	F	V	H	R	D	L	A	A	R	N	V	L	V	S	E	D	N	V	A	K	V	S	D	F	G	L	T	K	.	.	.	.	.	.	.	.	.	.	E	A	G	K	L	P	V	K	W	T	A	P	E	A	L	R	E	K	K	F	S	T
Template Known Secondary structure																				T	T		B		S				G	G	G					T	T									T	T		B	.	.	.	.	.	.	.	.	.	.							T	T	T	S						T	T	T
Template Predicted Secondary structure																																																		.	.	.	.	.	.	.	.	.	.
Template SS confidence
		290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.											.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.
		592	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	S	D	V	W	A	F	G	I	L	M	W	E	V	F	S	L	G	K	Q	P	Y	D	L	Y	D	N	S	Q	V	V	L	K	V	S	Q	G	H	R	L	Y	R	P	H	L	A	S	D	T	I	Y	Q	I	M	Y	S	C	W	H	E	L	P	E	K	R	P	T	F	Q	Q	L	L	S	S	I	E	P	L	R	E
Query Conservation
Alig confidence
Template Conservation
Template Sequence		K	S	D	V	W	S	F	G	I	L	L	W	E	I	Y	S	F	G	R	V	P	Y	P	R	I	P	L	K	D	V	V	P	R	V	E	K	G	Y	K	M	D	A	P	D	G	C	P	P	A	V	Y	D	V	M	K	N	C	W	H	L	D	A	A	T	R	P	T	F	L	Q	L	R	E	Q	L	E	H	I	R	T
Template Known Secondary structure																	T	T	T			S	S	T	T	S		T	T	T						T	T	T							T	T													T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		366	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.
		672	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	D	K	H
Query Conservation
Alig confidence
Template Conservation
Template Sequence		H	E	L	H
Template Known Secondary structure			T	T	T
Template Predicted Secondary structure
Template SS confidence
		446	.	.	.