|   |   |
12 | . | . | . | . | . | . | . | 20 | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . |
| Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Q | T | V | L | G | S | I | D | H | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | Y | T | G | S | G | Y | R | I | R | Y | S | E | L | Q | K | I | H | K | A | A | V | K | G | D | A | A | E | M | E | R | C | L | A | R | . |
. |
. |
. |
. |
. |
. |
R | S | G | D | L | D | A | L | D | K | Q | H | R | T | A | L | H | L |
| Query Conservation |   |
  |   |   |
|   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . |
|
|   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |   |
|
|   |   |
|   |   |   |   |
|   |   |
|
|   |   | . | . | . | . | . | . | . |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|
|
|
|   |
|
|   |   |   |
|   |   |   |
|
|   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |
|   |
|
|
|
|   |
|   |   |   |
|   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
E | S | P | I | K | L | H | T | E | A | A | G | S | Y | A | I | T | E | P | I | T | R | E | S | V | N | I | I | D | P | R | H | N | R | T | V | L | H | W | I | A | S | N | S | S | A | E | K | S | E | D | L | I | V | H | E | A | K | E | C | I | A | A | G | A | D | V | N | A | X | D | C | D | E | N | T | P | L | X | L |
| Template Known Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  | S | S | S |
|
|
| S |
|
| S | T | T | T | T | T | T |
|
|
| S | S |
|
|
|  |  |  |  |  |  |
| T | T |
|
| S |
|
| T | T |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
| T | T |
|
|
| T | T | S |
|
|  |  |  |  |
| Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
1021 | . | . | . | . | . | . | . | . | 1030 | . | . | . | . | . | . | . | . | . | 1040 | . | . | . | . | . | . | . | . | . | 1050 | . | . | . | . | . | . | . | . | . | 1060 | . | . | . | . | . | . | . | . | . | 1070 | . | . | . | . | . | . | . | . | . | 1080 | . | . | . | . | . | . | . | . | . | 1090 | . | . | . | . | . | . | . | . | . | 1100 |
|   |
|   |   |
74 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Predicted Secondary structure |   |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Query SS confidence |   |
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
| Query Sequence |   |
A | C | A | S | G | H | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
| Query Conservation |   |
  |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Alig confidence |   |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
A | V | L | A | R | R | R | R | L | V | A | Y | L | X | K | A | G | A | D | P | T | I | Y | N | K | S | E | R | S | A | L | H | Q | A | A | A | N | R | D | F | G | X | X | V | Y | X | L | N | S | T | K | L | K | G | D | I | E | E | L | D | R | N | G | X | T | A | L | X | I | V | A | H | N | E | G | R | D | Q | V | A |
| Template Known Secondary structure |   |
 |  |  |  | T |
|  |  |  |  |  |  |  |  |  | T | T |
|
| S |
|
|
|
| T | T |
|
|
|  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  | T | T | S |  |  |  |  |  | T | T | S |
|
|
| T | T | S |
|
|  |  |  |  |  |  |  | S |
| S | T | T |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
1101 | . | . | . | . | . | . | . | . | 1110 | . | . | . | . | . | . | . | . | . | 1120 | . | . | . | . | . | . | . | . | . | 1130 | . | . | . | . | . | . | . | . | . | 1140 | . | . | . | . | . | . | . | . | . | 1150 | . | . | . | . | . | . | . | . | . | 1160 | . | . | . | . | . | . | . | . | . | 1170 | . | . | . | . | . | . | . | . | . | 1180 |
|   |
|   |   |
|
|
|
|
|
|
|
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . |
| Predicted Secondary structure |   |
. | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
| Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
V | K | V | V | T | L | L | V | N | R | K | C | Q | I | D | I | Y | D | K | E | N | R | T | P | L | I | Q | A | V | H | C | Q | E | E | A | C | A | V | I | L | L | E | H | G | A | N | P | N | L | K | D | I | Y | G | N | T | A | L | H | Y | A | V | Y | S | E | S | T | S | L | A | E | K | L |
| Query Conservation |   |
. | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |
|   |   |   |
|   |   |
|
|
|   |   |
|
| Alig confidence |   |
. | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |   |
|   |   |   |   |
|   |   |
|
| Template Sequence |   |
S | A | K | L | L | V | E | K | G | A | K | V | D | Y | D | G | A | A | R | K | D | S | E | K | Y | K | G | R | T | A | L | H | Y | A | A | Q | V | S | N | X | P | I | V | K | Y | L | V | G | E | K | G | S | N | K | D | K | Q | D | E | D | G | K | T | P | I | X | L | A | A | Q | E | G | R | I | E | V | V | X | Y | L |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T |
|
| S | S |
|
| S | G | G | G | T | S | S | S | S |
|
|
|
|
| T |  |  |  |  |  | S | S |
|
|  |  |  |  |  |  |  |  |  |  | S |
|
|
| T | T |
|
|
| T | T |
|
|
|  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
1181 | . | . | . | . | . | . | . | . | 1190 | . | . | . | . | . | . | . | . | . | 1200 | . | . | . | . | . | . | . | . | . | 1210 | . | . | . | . | . | . | . | . | . | 1220 | . | . | . | . | . | . | . | . | . | 1230 | . | . | . | . | . | . | . | . | . | 1240 | . | . | . | . | . | . | . | . | . | 1250 | . | . | . | . | . | . | . | . | . | 1260 |
|   |
|   |   |
153 | . | . | . | . | . | . | 160 | . | . | . | . |
| Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | F | H | G | E | N | I | E | A | L | D | K |
| Query Conservation |   |
|   |   |
|
|
|
|
|   |   |
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |
|
|
|
|
|   |   |
|   |
| Template Sequence |   |
I | Q | Q | G | A | S | V | E | A | V | D | A |
| Template Known Secondary structure |   |
 |  | T | T |
|
| S | S |
|
|
| S |
| Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
1261 | . | . | . | . | . | . | . | . | 1270 | . | . |
|   |