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Job DescriptionP42685
Confidence100.00%DateTue Apr 3 14:35:51 BST 2012
Rank49Aligned Residues257
% Identity45%Templatec3sxrA_
PDB info PDB header:transferase/transferase inhibitorChain: A: PDB Molecule:cytoplasmic tyrosine-protein kinase bmx; PDBTitle: crystal structure of bmx non-receptor tyrosine kinase complex with2 dasatinib
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   226...230.........240.........250.........260.........270.........280.........290.........300.....
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Query Sequence  QWEIDRNSIQLLKRLGSGQFGEVWEGLWNNTTPVAVKTLKPGSMDPNDFLREAQIMKNLRHPKLIQLYAVCTLEDPIYII
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Template Sequence  HMELKREEITLLKELGSVVKLGKW. . . . KGQYDVAVKMIKEGSMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKEYPIYIV
Template Known Secondary structure 

B

GGG

....TTT
BTTB
S

TTB


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   409410.........420.........430.. .......440.........450.........460.........470.........480....
 
   306...310.........320.........330.........340.........350.........360.........370.........380.....
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Query Sequence  TELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLESRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNED
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Template Sequence  TEYISNGCLLNYLRSH. GKGLEPSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLDDQ. .
Template Known Secondary structure 

TT
B.GGGS
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SGGG
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TT
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   489490.........500.... .....510.........520.........530.........540.........550.........560.....
 
   386...390.........400.........410.........420.........430.........440.........450.........460.....
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Query Sequence  IYESRHEIKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYRLPQPSNCPQQFYNI
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Template Conservation  .                            

 
 
 
  

 
 
               
                  
Template Sequence  . YVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKMPYDLYTNSEVVLKVSQGHRLYRPHLASDTIYQI
Template Known Secondary structure  .

S



GGG

STTTTS

TTTT

T





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   566...570.........580.........590.........600.........610.........620.........630.........640....
 
   466...470.........480.........490
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Query Sequence  MLECWNAEPKERPTFETLRWKLEDY
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Template Sequence  MYSCWHELPEKRPTFQQLLSSIEPL
Template Known Secondary structure  TT
SSGGGS

GGG
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   645....650.........660.........
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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