Job Description P42685 Confidence 100.00% Date Tue Apr 3 14:35:51 BST 2012 Rank 156 Aligned Residues 254 % Identity 26% Template c3mtfB_ PDB info PDB header:transferase Chain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor Resolution 2.15 Å

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		232	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.					.	.	.	.	300	.	.	.	.	.	.	.
Predicted Secondary structure																																																																		.	.	.	.
Query SS confidence																																																																		.	.	.	.
Query Sequence		N	S	I	Q	L	L	K	R	L	G	S	G	Q	F	G	E	V	W	E	G	L	W	N	N	T	T	P	V	A	V	K	T	L	K	P	G	S	M	D	P	N	D	F	L	R	E	A	Q	I	M	K	N	L	R	H	P	K	L	I	Q	L	Y	A	V	.	.	.	.	C	T	L	E	D	P	I	Y	I	I	T	E
Query Conservation																																																																		.	.	.	.
Alig confidence																								.																																										.	.	.	.
Template Conservation																								.
Template Sequence		R	D	I	T	L	L	E	C	V	G	K	G	R	Y	G	E	V	W	R	G	S	W	.	Q	G	E	N	V	A	V	K	I	F	S	S	R	D	E	K	S	W	F	R	E	T	E	L	Y	N	T	V	M	L	R	H	E	N	I	L	G	F	I	A	S	D	M	T	S	R	H	S	S	T	Q	L	W	L	I	T	H
Template Known Secondary structure		T	T											T	T									.	T	T										G	G	G														S					T	T	B												T	T
Template Predicted Secondary structure																								.
Template SS confidence
		206	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.		.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.
		308	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350									.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																													.	.	.	.	.	.	.	.
Query SS confidence																																													.	.	.	.	.	.	.	.
Query Sequence		L	M	R	H	G	S	L	Q	E	Y	L	Q	N	D	T	G	S	K	I	H	L	T	Q	Q	V	D	M	A	A	Q	V	A	S	G	M	A	Y	L	E	S	R	N	Y	.	.	.	.	.	.	.	.	I	H	R	D	L	A	A	R	N	V	L	V	G	E	H	N	I	Y	K	V	A	D	F	G	L	A	R	V	F
Query Conservation																																													.	.	.	.	.	.	.	.
Alig confidence																	.	.	.																										.	.	.	.	.	.	.	.
Template Conservation																	.	.	.
Template Sequence		Y	H	E	M	G	S	L	Y	D	Y	L	Q	L	T	T	.	.	.	L	D	T	V	S	C	L	R	I	V	L	S	I	A	S	G	L	A	H	L	H	I	E	I	F	G	T	Q	G	K	P	A	I	A	H	R	D	L	K	S	K	N	I	L	V	K	K	N	G	Q	C	C	I	A	D	L	G	L	A	V	M	H
Template Known Secondary structure				T	T		B										.	.	.	B																					S		B		S	T	T		B						S			S	G	G	G					T	T	S								T	T
Template Predicted Secondary structure																	.	.	.
Template SS confidence
		285	.	.	.	.	290	.	.	.	.	.	.	.	.	.				300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.
		380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.							410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																.	.	.	.	.	.																															.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																.	.	.	.	.	.																															.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		K	V	D	N	E	D	I	Y	E	S	R	H	E	I	K	L	P	V	K	W	T	A	P	E	A	I	R	S	N	K	.	.	.	.	.	.	F	S	I	K	S	D	V	W	S	F	G	I	L	L	Y	E	I	I	T	Y	G	K	M	P	Y	S	G	M	T	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																																.	.	.	.	.	.																															.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																																.	.	.	.	.	.																				.											.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																									.
Template Sequence		S	Q	S	T	N	Q	L	D	V	G	N	N	P	R	V	G	T	K	R	Y	M	A	P	E	V	L	D	E	T	I	Q	V	D	C	F	D	S	Y	K	R	V	D	I	W	A	F	G	L	V	L	W	E	V	A	R	.	R	M	V	S	N	G	I	V	E	D	Y	K	P	P	F	Y	D	V	V	P	N	D	P	S
Template Known Secondary structure			T	T	T	T													G	G	G							T	T				T	T																						T	.	T	B		B	T	T	B							T	T	T	T	T	S		S	S
Template Predicted Secondary structure																																																									.
Template SS confidence
		362	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.		.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440
			440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.							.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490
Predicted Secondary structure		.																			.	.	.	.	.	.
Query SS confidence		.																			.	.	.	.	.	.
Query Sequence		.	A	Q	V	I	Q	M	L	A	Q	N	Y	R	L	P	Q	P	S	N	.	.	.	.	.	.	C	P	Q	Q	F	Y	N	I	M	L	E	C	W	N	A	E	P	K	E	R	P	T	F	E	T	L	R	W	K	L	E	D	Y
Query Conservation		.																			.	.	.	.	.	.
Alig confidence		.																			.	.	.	.	.	.
Template Conservation
Template Sequence		F	E	D	M	R	K	V	V	C	V	D	Q	Q	R	P	N	I	P	N	R	W	F	S	D	P	T	L	T	S	L	A	K	L	M	K	E	C	W	Y	Q	N	P	S	A	R	L	T	A	L	R	I	K	K	T	L	T	K	I
Template Known Secondary structure										T	T	S								G	G	G	G	G	S																S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		441	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions