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Job DescriptionP42685
Confidence100.00%DateTue Apr 3 14:35:51 BST 2012
Rank17Aligned Residues271
% Identity38%Templatec3g0eA_
PDB info PDB header:transferaseChain: A: PDB Molecule:mast/stem cell growth factor receptor; PDBTitle: kit kinase domain in complex with sunitinib
Resolution1.60 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   222.......230.........240.........250... ......260.........270. ........280.... .....290..
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Query Sequence  KTVDQWEIDRNSIQLLKRLGSGQFGEVWEGLW. . . . . . NNTTPVAVKTLKPGSMDP. . NDFLREAQIMKNL. RHPKLIQL
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Template Sequence  PYDHKWEFPRNRLSFGKTLGAGAFGKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNL
Template Known Secondary structure 


GGGB

GGG
SSSSSSTT

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TTB

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   577..580.........590.........600.........610.........620.........630.........640.........650......
 
   293......300.........310.........320 .........330.........340.........350......
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Query Sequence  YAVCTLEDPIYIITELMRHGSLQEYLQN. . . . . . . . . . . . . . . . DTGSKIHLTQQVDMAAQVASGMAYLESRNYIHRDLA
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Template Sequence  LGACTIGGPTLVITEYCCYGDLLNFLRRKRDSFICSKTSPAIMEDDELALDLEDLLSFSYQVAKGMAFLASKNCIHRDLA
Template Known Secondary structure 
SSSS


TT
BGGGGS
SSS



BTTB




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S
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   657..660.........670.........680.........690.........700.........710.........720.........730......
 
   357..360.........370.........380.........390.........400.........410.........420.........430......
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Query Sequence  ARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSG
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Template Sequence  ARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARL. . PVKWMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPG
Template Known Secondary structure  GGGTTT


GGG

GGG
TTSTT..
GGGS
T


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   795....800.........810.........820.........830. ........840.........850.........860.........870..
 
   437. .440.........450.........460.........470.........480.........490....
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Query Sequence  MT. GAQVIQMLAQNYRLPQPSNCPQQFYNIMLECWNAEPKERPTFETLRWKLEDYFETD
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Template Sequence  MPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISES
Template Known Secondary structure 


STT





TT

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   873......880.........890.........900.........910.........920.........930.
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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