Job Description P42685 Confidence 100.00% Date Tue Apr 3 14:35:51 BST 2012 Rank 193 Aligned Residues 261 % Identity 33% Template c3c1xA_ PDB info PDB header:transferase Chain: A: PDB Molecule:hepatocyte growth factor receptor; PDBTitle: crystal structure of the tyrosine kinase domain of the2 hepatocyte growth factor receptor c-met in complex with a3 pyrrolotriazine based inhibitor Resolution 2.17 Å

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		222	.	.	.	.	.	.	.	230	.	.	.			.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.					.	.	260	.	.	.	.	.	.	.	.	.	270			.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.
Predicted Secondary structure														.	.																									.	.	.	.														.	.
Query SS confidence														.	.																									.	.	.	.														.	.
Query Sequence		K	T	V	D	Q	W	E	I	D	R	N	S	.	.	I	Q	L	L	K	R	L	G	S	G	Q	F	G	E	V	W	E	G	L	W	N	N	T	T	.	.	.	.	P	V	A	V	K	T	L	K	P	G	S	M	D	.	.	P	N	D	F	L	R	E	A	Q	I	M	K	N	L	R	H	P	K	L	I	Q	L	Y
Query Conservation														.	.																									.	.	.	.														.	.
Alig confidence														.	.																									.	.	.	.														.	.
Template Conservation
Template Sequence		Q	A	V	Q	H	V	V	I	G	P	S	S	L	I	V	H	F	N	E	V	I	G	R	G	H	F	G	C	V	Y	H	G	T	L	L	D	N	D	G	K	K	I	H	C	A	V	K	S	L	N	R	I	T	D	I	G	E	V	S	Q	F	L	T	E	G	I	I	M	K	D	F	S	H	P	N	V	L	S	L	L
Template Known Secondary structure			T	T	T	T	T	B			S	T	T													S	S	S										T	T	T												S		S		S											T	T	S	T	T				T	T	B
Template Predicted Secondary structure
Template SS confidence
		1064	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.
		294	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	V	C	T	L	E	D	P	I	Y	I	I	T	E	L	M	R	H	G	S	L	Q	E	Y	L	Q	N	D	T	G	S	K	I	H	L	T	Q	Q	V	D	M	A	A	Q	V	A	S	G	M	A	Y	L	E	S	R	N	Y	I	H	R	D	L	A	A	R	N	V	L	V	G	E	H	N	I	Y	K	V	A	D	F
Query Conservation
Alig confidence
Template Conservation
Template Sequence		G	I	C	L	R	S	E	G	S	P	L	V	V	L	P	Y	M	K	H	G	D	L	R	N	F	I	R	N	E	T	H	N	P	T	V	K	D	L	I	G	F	G	L	Q	V	A	K	G	M	K	F	L	A	S	K	K	F	V	H	R	D	L	A	A	R	N	C	M	L	D	E	K	F	T	V	K	V	A	D	F
Template Known Secondary structure								S	S										T	T		B								T	T				B																					T	T				S				G	G	G					T	T
Template Predicted Secondary structure
Template SS confidence
		1144	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.	.	.	.	.	.	.	1180	.	.	.	.	.	.	.	.	.	1190	.	.	.	.	.	.	.	.	.	1200	.	.	.	.	.	.	.	.	.	1210	.	.	.	.	.	.	.	.	.	1220	.	.	.
		374	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	L	A	R	V	F	K	V	D	N	E	D	I	Y	E	S	R	H	E	I	K	L	P	V	K	W	T	A	P	E	A	I	R	S	N	K	F	S	I	K	S	D	V	W	S	F	G	I	L	L	Y	E	I	I	T	Y	G	K	M	P	Y	S	G	M	T	G	A	Q	V	I	Q	M	L	A	Q	N	Y	R	L	P
Query Conservation
Alig confidence					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		L	P	V	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	K	W	M	A	L	E	S	L	Q	T	Q	K	F	T	T	K	S	D	V	W	S	F	G	V	L	L	W	E	L	M	T	R	G	A	P	P	Y	P	D	V	N	T	F	D	I	T	V	Y	L	L	Q	G	R	R	L	L
Template Known Secondary structure				G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	G	S																												T	T	S			S		T	T	S		S	S								T	T
Template Predicted Secondary structure					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		1245	.	.																						.	.	1250	.	.	.	.	.	.	.	.	.	1260	.	.	.	.	.	.	.	.	.	1270	.	.	.	.	.	.	.	.	.	1280	.	.	.	.	.	.	.	.	.	1290	.	.	.	.	.	.	.	.	.	1300	.	.	.
		454	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	P	S	N	C	P	Q	Q	F	Y	N	I	M	L	E	C	W	N	A	E	P	K	E	R	P	T	F	E	T	L	R	W	K	L	E	D	Y	F	E	T	D	S	S	Y	S	D	A	N	N	F
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Q	P	E	Y	C	P	D	P	L	Y	E	V	M	L	K	C	W	H	P	K	A	E	M	R	P	S	F	S	E	L	V	S	R	I	S	A	I	F	S	T	F	I	G	E	H	Y	V	H	V	N
Template Known Secondary structure				T	T													T		S	S	G	G	G	S																T			S			B
Template Predicted Secondary structure
Template SS confidence
		1304	.	.	.	.	.	1310	.	.	.	.	.	.	.	.	.	1320	.	.	.	.	.	.	.	.	.	1330	.	.	.	.	.	.	.	.	.	1340	.	.	.	.	.	.	.	.	.	1350	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions