Job Description P42685 Confidence 100.00% Date Tue Apr 3 14:35:51 BST 2012 Rank 247 Aligned Residues 257 % Identity 21% Template c2vagA_ PDB info PDB header:transferase Chain: A: PDB Molecule:dual specificity protein kinase clk1; PDBTitle: crystal structure of di-phosphorylated human clk1 in2 complex with a novel substituted indole inhibitor Resolution 1.80 Å

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		228	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.			.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.							290	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																													.	.																																				.	.	.	.	.	.
Query SS confidence																													.	.																																				.	.	.	.	.	.
Query Sequence		E	I	D	R	N	S	I	Q	L	L	K	R	L	G	S	G	Q	F	G	E	V	W	E	G	L	W	N	.	.	N	T	T	P	V	A	V	K	T	L	K	P	G	S	M	D	P	N	D	F	L	R	E	A	Q	I	M	K	N	L	R	H	P	K	L	.	.	.	.	.	.	I	Q	L	Y	A	V	C	T	L	E
Query Conservation																													.	.																																				.	.	.	.	.	.
Alig confidence																													.	.																																				.	.	.	.	.	.
Template Conservation
Template Sequence		D	V	L	S	A	R	Y	E	I	V	D	T	L	G	E	G	A	F	G	K	V	V	E	C	I	D	H	K	A	G	G	R	H	V	A	V	K	I	V	K	N	V	D	R	Y	C	E	A	A	R	S	E	I	Q	V	L	E	H	L	N	T	T	D	P	N	S	T	F	R	C	V	Q	M	L	E	W	F	E	H	H
Template Known Secondary structure					T	T	T											T	T									T	T	T	T	T										S	S																						T	T		T	T		B										T
Template Predicted Secondary structure
Template SS confidence
		155	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.
		300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	P	I	Y	I	I	T	E	L	M	R	H	G	S	L	Q	E	Y	L	Q	N	D	T	G	S	K	I	H	L	T	Q	Q	V	D	M	A	A	Q	V	A	S	G	M	A	Y	L	E	S	R	N	Y	I	H	R	D	L	A	A	R	N	V	L	V	G	E	H	N	I	Y	K	V	A	D	F	G	L	A	R	V	F
Query Conservation
Alig confidence														.
Template Conservation														.
Template Sequence		G	H	I	C	I	V	F	E	L	L	G	L	.	S	T	Y	D	F	I	K	E	N	G	F	L	P	F	R	L	D	H	I	R	K	M	A	Y	Q	I	C	K	S	V	N	F	L	H	S	N	K	L	T	H	T	D	L	K	P	E	N	I	L	F	V	Q	S	D	Y	T	E	A	Y	N	K	R	D	E	R	T	L
Template Known Secondary structure		T												.	B								T	T	T																									T	T								G	G	G				S
Template Predicted Secondary structure														.
Template SS confidence
		235	.	.	.	.	240	.	.	.	.	.	.		.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.
		380	.	.	.	.	.	.	.	.								.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.
Predicted Secondary structure											.	.	.	.	.	.	.																																																													.	.	.	.
Query SS confidence											.	.	.	.	.	.	.																																																													.	.	.	.
Query Sequence		K	V	D	N	E	D	I	Y	E	.	.	.	.	.	.	.	S	R	H	E	I	K	L	P	V	K	W	T	A	P	E	A	I	R	S	N	K	F	S	I	K	S	D	V	W	S	F	G	I	L	L	Y	E	I	I	T	Y	G	K	M	P	Y	S	G	M	T	G	A	Q	V	I	Q	M	L	A	Q	.	.	.	.
Query Conservation											.	.	.	.	.	.	.																																																													.	.	.	.
Alig confidence											.	.	.	.	.	.	.																																									.																				.	.	.	.
Template Conservation																																																										.
Template Sequence		I	N	P	D	I	K	V	V	D	F	G	S	A	T	Y	D	D	E	H	H	S	T	L	V	R	H	Y	R	A	P	E	V	I	L	A	L	G	W	S	Q	P	C	D	V	W	S	I	G	C	I	L	I	E	Y	Y	L	.	G	F	T	V	F	P	T	H	D	S	K	E	H	L	A	M	M	E	R	I	L	G	P
Template Known Secondary structure		S										S	S				T	T	S				S					S							T	T	S			S	T																	.	S	S		S				S															S
Template Predicted Secondary structure																																																										.
Template SS confidence
		317	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.		.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.
																																									449	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	N	Y	R	L	P	Q	P	S	N	C	P	Q	Q	F	Y	N	I	M	L	E	C	W	N	A	E	P	K	E	R	P	T	F	E	T	L	R	W	K
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		L	P	K	H	M	I	Q	K	T	R	K	R	K	Y	F	H	H	D	R	L	D	W	D	E	H	S	S	A	G	R	Y	V	S	R	A	C	K	P	L	K	E	F	M	L	S	Q	D	V	E	H	E	R	L	F	D	L	I	Q	K	M	L	E	Y	D	P	A	K	R	I	T	L	R	E	A	L	K	H
Template Known Secondary structure											S		G	G	G			T	T						T	T	S													G	G	G	G		S			S														T		S	S	T	T	T	S							T	T	S
Template Predicted Secondary structure
Template SS confidence
		398	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions