Job Description P42685 Confidence 100.00% Date Tue Apr 3 14:35:51 BST 2012 Rank 114 Aligned Residues 240 % Identity 23% Template c2r7bA_ PDB info PDB header:signaling protein, transferase Chain: A: PDB Molecule:phosphoinositide-dependent protein kinase 1; PDBTitle: crystal structure of the phosphoinositide-dependent kinase-2 1 (pdk-1)catalytic domain bound to a dibenzonaphthyridine3 inhibitor Resolution 2.70 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.		.	.	.	.	.	.	260	.	.	.	.	.					.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.
Predicted Secondary structure																										.													.	.	.	.
Query SS confidence																										.													.	.	.	.
Query Sequence		D	R	N	S	I	Q	L	L	K	R	L	G	S	G	Q	F	G	E	V	W	E	G	L	W	.	N	N	T	T	P	V	A	V	K	T	L	K	.	.	.	.	P	G	S	M	D	P	N	D	F	L	R	E	A	Q	I	M	K	N	L	R	H	P	K	L	I	Q	L	Y	A	V	C	T	L	E	D	P	I	Y	I
Query Conservation																										.													.	.	.	.
Alig confidence																										.													.	.	.	.
Template Conservation
Template Sequence		R	P	E	D	F	K	F	G	K	I	L	G	E	G	S	F	S	T	V	V	L	A	R	E	L	A	T	S	R	E	Y	A	I	K	I	L	E	K	R	H	I	I	K	E	N	K	V	P	Y	V	T	R	E	R	D	V	M	S	R	L	D	H	P	F	F	V	K	L	Y	F	T	F	Q	D	D	E	K	L	Y	F
Template Known Secondary structure			G	G	G											S	S									T	T	T																	T	T														T				T	T	B										S	S
Template Predicted Secondary structure
Template SS confidence
		78	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.
		305	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	T	E	L	M	R	H	G	S	L	Q	E	Y	L	Q	N	D	T	G	S	K	I	H	L	T	Q	Q	V	D	M	A	A	Q	V	A	S	G	M	A	Y	L	E	S	R	N	Y	I	H	R	D	L	A	A	R	N	V	L	V	G	E	H	N	I	Y	K	V	A	D	F	G	L	A	R	V	F	K	V	D	N	E
Query Conservation
Alig confidence																			.	.																																																													.
Template Conservation																			.	.																																																													.
Template Sequence		G	L	S	Y	A	K	N	G	E	L	L	K	Y	I	R	K	I	.	.	G	S	F	D	E	T	C	T	R	F	Y	T	A	E	I	V	S	A	L	E	Y	L	H	G	K	G	I	I	H	R	D	L	K	P	E	N	I	L	L	N	E	D	M	H	I	Q	I	T	D	F	G	T	A	K	V	L	F	V	G	T	.
Template Known Secondary structure							T	T		B								S	.	.	S	S																							T	T								T	T	T					T	T	S								T	T									.
Template Predicted Secondary structure																			.	.																																																													.
Template SS confidence
		158	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.			.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.
		385	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	I	Y	E	S	R	H	E	I	K	L	P	V	K	W	T	A	P	E	A	I	R	S	N	K	F	S	I	K	S	D	V	W	S	F	G	I	L	L	Y	E	I	I	T	Y	G	K	M	P	Y	S	G	M	T	G	A	Q	V	I	Q	M	L	A	Q	N	Y	R	L	P	Q	P	S	N	C	P	Q	Q	F	Y	N
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.																																	.																						.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.																																	.																						.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	A	Q	Y	V	S	P	E	L	L	T	E	K	S	A	C	K	S	S	D	L	W	A	L	G	C	I	I	Y	Q	L	V	A	.	G	L	P	P	F	R	A	G	N	E	Y	L	I	F	Q	K	I	I	K	L	E	.	Y	D	F	P	E	K	F	F	P	K	A	R	D
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	G	G	G								S	S																					.	S	S		S				S	S											T		.					S	S	S
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.																																	.																						.
Template SS confidence
														246	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.		.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.		.	300	.	.	.	.	.	.	.	.	.	310	.
		465	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	M	L	E	C	W	N	A	E	P	K	E	R	P	T	F	E	T	L	R	W	K
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	V	E	K	L	L	V	L	D	A	T	K	R	L	G	C	E	E	M	E	G	Y
Template Known Secondary structure					T	T	S		S	S	T	T	S	S	T	T	S	G	G	G	T	T
Template Predicted Secondary structure
Template SS confidence
		312	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions