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Job DescriptionP42685
Confidence100.00%DateTue Apr 3 14:35:51 BST 2012
Rank16Aligned Residues266
% Identity38%Templatec2ivsA_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase receptor PDBTitle: crystal structure of non-phosphorylated ret tyrosine kinase2 domain
Resolution2.00 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   224.....230.........240.........250... ......260...... ...270.........280.........290.....
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Query Sequence  VDQWEIDRNSIQLLKRLGSGQFGEVWEGLW. . . . . . NNTTPVAVKTLKP. . GSMDPNDFLREAQIMKNLRHPKLIQLYAV
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Template Sequence  DPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGA
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GGG
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   714.....720.........730.........740.........750.........760.........770.........780.........790...
 
   296...300.........310.........320... ......330.........340.........350.........360.........
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Query Sequence  CTLEDPIYIITELMRHGSLQEYLQNDTG. . . . . . SKIHLTQQVDMAAQVASGMAYLESRNYIHRDLAARNVLVGEHNIYK
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Template Sequence  CSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLRALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMK
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SGGGTTT
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   794.....800.........810.........820.........830.........840.........850.........860.........870...
 
   370.........380.........390.........400.........410.........420.........430.........440.........
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Query Sequence  VADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQN
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Template Sequence  ISDFGLSRDVYEEDS. . YVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTG
Template Known Secondary structure 


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   890.........900.... .....910.........920.........930.........940.........950.........960.......
 
   450.........460.........470.........480.........490.
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Query Sequence  YRLPQPSNCPQQFYNIMLECWNAEPKERPTFETLRWKLEDYF
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Template Sequence  HRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMM
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TT

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   968.970.........980.........990.........1000.........
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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