Job Description P42685 Confidence 100.00% Date Tue Apr 3 14:35:51 BST 2012 Rank 5 Aligned Residues 424 % Identity 55% Template c2c0iA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983 Resolution 2.30 Å

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		46	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	F	V	A	L	F	D	Y	Q	A	R	T	A	E	D	L	S	F	R	A	G	D	K	L	Q	V	L	D	T	L	H	E	G	W	W	F	A	R	H	L	E	K	R	R	D	G	S	S	Q	Q	L	Q	G	Y	I	P	S	N	Y	V	A	E	D	R	S	L	Q	A	E	P	W	F	F	G	A	I	G	R	S	D
Query Conservation
Alig confidence																															.													.	.	.	.	.	.	.
Template Conservation																															.													.	.	.	.	.	.	.
Template Sequence		I	V	V	A	L	Y	D	Y	E	A	I	H	H	E	D	L	S	F	Q	K	G	D	Q	M	V	V	L	E	E	.	S	G	E	W	W	K	A	R	S	L	A	T	.	.	.	.	.	.	.	R	K	E	G	Y	I	P	S	N	Y	V	A	R	V	D	S	L	E	T	E	E	W	F	F	K	G	I	S	R	K	D
Template Known Secondary structure						S	S		B				S	S	S	B			B		T	T									.		T	T							T	T	T	.	.	.	.	.	.	.								G	G	G				T	T	S	G	G	G	S	T	T			T	T
Template Predicted Secondary structure																															.													.	.	.	.	.	.	.
Template SS confidence
		61	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.		90	.	.	.	.	.	.	.	.	.	100	.								.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.
		126	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.						.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200
Predicted Secondary structure																																		.	.	.	.	.
Query SS confidence																																		.	.	.	.	.
Query Sequence		A	E	K	Q	L	L	Y	S	E	N	K	T	G	S	F	L	I	R	E	S	E	S	Q	K	G	E	F	S	L	S	V	L	.	.	.	.	.	D	G	A	V	V	K	H	Y	R	I	K	R	L	D	E	G	G	F	F	L	T	R	R	R	I	F	S	T	L	N	E	F	V	S	H	Y	T	K	T	S	D	G	L
Query Conservation																																		.	.	.	.	.
Alig confidence																																		.	.	.	.	.
Template Conservation
Template Sequence		A	E	R	Q	L	L	A	P	G	N	M	L	G	S	F	M	I	R	D	S	E	T	T	K	G	S	Y	S	L	S	V	R	D	Y	D	P	R	Q	G	D	T	V	K	H	Y	K	I	R	T	L	D	N	G	G	F	Y	I	S	P	R	S	T	F	S	T	L	Q	E	L	V	D	H	Y	K	K	G	N	D	G	L
Template Known Secondary structure							T	S	T	T			T	T								S	S	S	T	T											T	T	T										B			S	T	T				S	S	T	T	S			S	S								T	T	S	S		S	S
Template Predicted Secondary structure
Template SS confidence
		133	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.
		201	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Predicted Secondary structure
Query SS confidence
Query Sequence		C	V	K	L	G	K	P	C	L	K	I	Q	V	P	A	P	F	D	L	S	Y	K	T	V	D	Q	W	E	I	D	R	N	S	I	Q	L	L	K	R	L	G	S	G	Q	F	G	E	V	W	E	G	L	W	N	N	T	T	P	V	A	V	K	T	L	K	P	G	S	M	D	P	N	D	F	L	R	E	A	Q	I
Query Conservation
Alig confidence																					.	.	.	.	.
Template Conservation																					.	.	.	.	.
Template Sequence		C	Q	K	L	S	V	P	C	M	S	S	K	P	Q	K	P	W	E	K	.	.	.	.	.	D	A	W	E	I	P	R	E	S	L	K	L	E	K	K	L	G	A	G	Q	F	G	E	V	W	M	A	T	Y	N	K	H	T	K	V	A	V	K	T	M	K	P	G	S	M	S	V	E	A	F	L	A	E	A	N	V
Template Known Secondary structure		S	S				S	B												T	.	.	.	.	.	T		S	B			G	G	G											T	T									T	T	T												S	S
Template Predicted Secondary structure																					.	.	.	.	.
Template SS confidence
		213	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.						.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.
		281	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Predicted Secondary structure
Query SS confidence
Query Sequence		M	K	N	L	R	H	P	K	L	I	Q	L	Y	A	V	C	T	L	E	D	P	I	Y	I	I	T	E	L	M	R	H	G	S	L	Q	E	Y	L	Q	N	D	T	G	S	K	I	H	L	T	Q	Q	V	D	M	A	A	Q	V	A	S	G	M	A	Y	L	E	S	R	N	Y	I	H	R	D	L	A	A	R	N	V
Query Conservation
Alig confidence																		.
Template Conservation																		.
Template Sequence		M	K	T	L	Q	H	D	K	L	V	K	L	H	A	V	V	.	T	K	E	P	I	Y	I	I	T	E	F	M	A	K	G	S	L	L	D	F	L	K	S	D	E	G	S	K	Q	P	L	P	K	L	I	D	F	S	A	Q	I	A	E	G	M	A	F	I	E	Q	R	N	Y	I	H	R	D	L	R	A	A	N	I
Template Known Secondary structure				T				T	T	B								.		S	S	S									T	T		B							S	T	T	G	G	G																							T	T				S			S	G	G	G
Template Predicted Secondary structure																		.
Template SS confidence
		288	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.		.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.
		361	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440
Predicted Secondary structure
Query SS confidence
Query Sequence		L	V	G	E	H	N	I	Y	K	V	A	D	F	G	L	A	R	V	F	K	V	D	N	E	D	I	Y	E	S	R	H	E	I	K	L	P	V	K	W	T	A	P	E	A	I	R	S	N	K	F	S	I	K	S	D	V	W	S	F	G	I	L	L	Y	E	I	I	T	Y	G	K	M	P	Y	S	G	M	T	G	A
Query Conservation
Alig confidence																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		L	V	S	A	S	L	V	C	K	I	A	D	F	G	L	A	R	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	V	I	P	I	K	W	T	A	P	E	A	I	N	F	G	S	F	T	I	K	S	D	V	W	S	F	G	I	L	L	M	E	I	V	T	Y	G	R	I	P	Y	P	G	M	S	N	P
Template Known Secondary structure					T	T								T	T	G	G	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	T			G	G	G	S																												T	T	T			S	S	T	T
Template Predicted Secondary structure																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		367	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.																	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430
		441	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	V	I	Q	M	L	A	Q	N	Y	R	L	P	Q	P	S	N	C	P	Q	Q	F	Y	N	I	M	L	E	C	W	N	A	E	P	K	E	R	P	T	F	E	T	L	R	W	K	L	E	D	Y	F	E	T	D	S	S	Y	S	D
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	V	I	R	A	L	E	R	G	Y	R	M	P	R	P	E	N	C	P	E	E	L	Y	N	I	M	M	R	C	W	K	N	R	P	E	E	R	P	T	F	E	Y	I	Q	S	V	L	D	D	F	Y	T	A	T	E	S	Q	E	E
Template Known Secondary structure									T	T							T	T													T		S	S	G	G	G	S												T	T	T	S		G	G	G
Template Predicted Secondary structure
Template SS confidence
		444	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.