Job Description P42685 Confidence 100.00% Date Tue Apr 3 14:35:51 BST 2012 Rank 2 Aligned Residues 443 % Identity 53% Template c1y57A_ PDB info PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor Resolution 1.91 Å

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		45	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		H	Y	F	V	A	L	F	D	Y	Q	A	R	T	A	E	D	L	S	F	R	A	G	D	K	L	Q	V	L	D	T	L	H	E	G	W	W	F	A	R	H	L	E	K	R	R	D	G	S	S	Q	Q	L	Q	G	Y	I	P	S	N	Y	V	A	E	D	R	S	L	Q	A	E	P	W	F	F	G	A	I	G	R	S
Query Conservation
Alig confidence																																													.	.	.	.	.	.	.
Template Conservation																																													.	.	.	.	.	.	.
Template Sequence		T	T	F	V	A	L	Y	D	Y	E	S	R	T	E	T	D	L	S	F	K	K	G	E	R	L	Q	I	V	N	N	T	E	G	D	W	W	L	A	H	S	L	S	T	.	.	.	.	.	.	.	G	Q	T	G	Y	I	P	S	N	Y	V	A	P	S	D	S	I	Q	A	E	E	W	Y	F	G	K	I	T	R	R
Template Known Secondary structure		T					S	S		B				S	S	S	B			B		T	T						S			S	S	S	S							T	T	T	.	.	.	.	.	.	.								G	G	G				T	T	S	G	G	G	S	T	T				S
Template Predicted Secondary structure																																													.	.	.	.	.	.	.
Template SS confidence
		84	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.								.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.
		125	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.						.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																				.	.	.	.	.
Query SS confidence																																				.	.	.	.	.
Query Sequence		D	A	E	K	Q	L	L	Y	S	E	N	K	T	G	S	F	L	I	R	E	S	E	S	Q	K	G	E	F	S	L	S	V	L	D	.	.	.	.	.	G	A	V	V	K	H	Y	R	I	K	R	L	D	E	G	G	F	F	L	T	R	R	R	I	F	S	T	L	N	E	F	V	S	H	Y	T	K	T	S	D	G
Query Conservation																																				.	.	.	.	.
Alig confidence																																				.	.	.	.	.
Template Conservation
Template Sequence		E	S	E	R	L	L	L	N	A	E	N	P	R	G	T	F	L	V	R	E	S	E	T	T	K	G	A	Y	C	L	S	V	S	D	F	D	N	A	K	G	L	N	V	K	H	Y	K	I	R	K	L	D	S	G	G	F	Y	I	T	S	R	T	Q	F	N	S	L	Q	Q	L	V	A	Y	Y	S	K	H	A	D	G
Template Known Secondary structure								T		T	T			T	T								S	S	S	T	T											T	T	T													S	S	S				S	S	T	T	S			S	S													T	T
Template Predicted Secondary structure
Template SS confidence
		157	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.
		200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	C	V	K	L	G	K	P	C	L	K	I	Q	V	P	A	P	F	D	L	S	Y	K	T	V	D	Q	W	E	I	D	R	N	S	I	Q	L	L	K	R	L	G	S	G	Q	F	G	E	V	W	E	G	L	W	N	N	T	T	P	V	A	V	K	T	L	K	P	G	S	M	D	P	N	D	F	L	R	E	A	Q
Query Conservation
Alig confidence																						.	.	.	.
Template Conservation																						.	.	.	.
Template Sequence		L	C	H	R	L	T	T	V	C	P	T	S	K	P	Q	T	Q	G	L	A	.	.	.	.	K	D	A	W	E	I	P	R	E	S	L	R	L	E	V	K	L	G	Q	G	C	F	G	E	V	W	M	G	T	W	N	G	T	T	R	V	A	I	K	T	L	K	P	G	T	M	S	P	E	A	F	L	Q	E	A	Q
Template Known Secondary structure		S	S	S					B									S	S			.	.	.	.			T	T	B			G	G	G											T	T									T	T	T										T	T	S	S
Template Predicted Secondary structure																						.	.	.	.
Template SS confidence
		237	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.					.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.
		280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	M	K	N	L	R	H	P	K	L	I	Q	L	Y	A	V	C	T	L	E	D	P	I	Y	I	I	T	E	L	M	R	H	G	S	L	Q	E	Y	L	Q	N	D	T	G	S	K	I	H	L	T	Q	Q	V	D	M	A	A	Q	V	A	S	G	M	A	Y	L	E	S	R	N	Y	I	H	R	D	L	A	A	R	N
Query Conservation
Alig confidence																				.
Template Conservation																				.
Template Sequence		V	M	K	K	L	R	H	E	K	L	V	Q	L	Y	A	V	V	S	.	E	E	P	I	Y	I	V	T	E	Y	M	S	K	G	S	L	L	D	F	L	K	G	E	T	G	K	Y	L	R	L	P	Q	L	V	D	M	A	A	Q	I	A	S	G	M	A	Y	V	E	R	M	N	Y	V	H	R	D	L	R	A	A	N
Template Known Secondary structure									T	T	B									.	S	S	S									T	T									S																												T	T				S			S	G	G	G
Template Predicted Secondary structure																				.
Template SS confidence
		313	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330		.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.
		360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	L	V	G	E	H	N	I	Y	K	V	A	D	F	G	L	A	R	V	F	K	V	D	N	E	D	I	Y	E	S	R	H	E	I	K	L	P	V	K	W	T	A	P	E	A	I	R	S	N	K	F	S	I	K	S	D	V	W	S	F	G	I	L	L	Y	E	I	I	T	Y	G	K	M	P	Y	S	G	M	T	G
Query Conservation
Alig confidence																										.	.	.
Template Conservation																										.	.	.
Template Sequence		I	L	V	G	E	N	L	V	C	K	V	A	D	F	G	L	A	R	L	I	E	D	N	E	.	.	.	Y	T	A	R	Q	G	A	K	F	P	I	K	W	T	A	P	E	A	A	L	Y	G	R	F	T	I	K	S	D	V	W	S	F	G	I	L	L	T	E	L	T	T	K	G	R	V	P	Y	P	G	M	V	N
Template Known Secondary structure						G	G	G								T	T						S	S		.	.	.					T	T	T	T		S	G	G	G	S																												T	T	S			S	S	T	T
Template Predicted Secondary structure																										.	.	.
Template SS confidence
		392	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.				.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.
		440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.		.	.	.	.	.	.	.	.	500	.	.
Predicted Secondary structure																																																						.
Query SS confidence																																																						.
Query Sequence		A	Q	V	I	Q	M	L	A	Q	N	Y	R	L	P	Q	P	S	N	C	P	Q	Q	F	Y	N	I	M	L	E	C	W	N	A	E	P	K	E	R	P	T	F	E	T	L	R	W	K	L	E	D	Y	F	.	E	T	D	S	S	Y	S	D	A	N	N
Query Conservation																																																						.
Alig confidence																																																						.
Template Conservation
Template Sequence		R	E	V	L	D	Q	V	E	R	G	Y	R	M	P	C	P	P	E	C	P	E	S	L	H	D	L	M	C	Q	C	W	R	K	E	P	E	E	R	P	T	F	E	Y	L	Q	A	F	L	E	D	Y	F	T	S	T	E	P	Q	Y	Q	P	G	E	N
Template Known Secondary structure										T	T							T	T													T		S	S	G	G	G	S												T					T		T	T					S
Template Predicted Secondary structure
Template SS confidence
		469	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.