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Job DescriptionP42685
Confidence100.00%DateTue Apr 3 14:35:51 BST 2012
Rank76Aligned Residues251
% Identity37%Templatec1xkkA_
PDB info PDB header:transferaseChain: A: PDB Molecule:epidermal growth factor receptor; PDBTitle: egfr kinase domain complexed with a quinazoline inhibitor-2 gw572016
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


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Query Sequence  IDRNSIQLLKRLGSGQFGEVWEGLW. NNTTPVAVKTLKPGSMDPNDFLREAQIMKNLRHPKLIQLYAVCTLEDPIYIITE
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Template Sequence  LKETEFKKIKVLGSGAFGTVYKGLWIPVKIPVAIKELRE. . KANKEILDEAYVMASVDNPHVCRLLGICLTSTV. QLITQ
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   707..710.........720.........730.........740..... ....750.........760.........770........ .780...
 
   308.310.........320.........330.........340.........350.........360.........370.........380.......
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Query Sequence  LMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLESRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIY
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Template Sequence  LMPFGCLLDYVREH. KDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEE. . . .
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   792.......800..... ....810.........820.........830.........840.........850.........860......
 
   388.390.........400.........410.........420.........430.........440.........450.........460.......
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Query Sequence  ESRHEIKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYRLPQPSNCPQQFYNIML
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Template Sequence  . . . . . . KVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMV
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   867..870.........880.........890.........900.........910.........920.........930.........940
 
   468.470.........480.........490...
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Query Sequence  ECWNAEPKERPTFETLRWKLEDYFET
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Template Sequence  KCWMIDADSRPKFRELIIEFSKMARD
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   949950.........960.........970....
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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