|   |   |
181 | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | |
|
. | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | |
|
|
|
| Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
| . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  | . | . | . | . |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
| Query Sequence |   |
W | D | D | W | E | R | P | R | E | E | F | T | L | C | R | K | L | G | S | G | Y | F | G | E | V | F | E | G | L | W | K | D | R | V | Q | V | A | I | K | V | I | S | R | D | . |
. |
N | L | L | H | Q | Q | M | L | Q | S | E | I | Q | A | M | K | K | L | R | H | K | H | I | L | A | L | Y | A | V | V | . |
. |
. |
. |
| Query Conservation |   |
  |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   | . | . |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|   |
|
|
|
|
|   |
|   |
|   |   | . | . | . | . |
| Alig confidence |   |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
| Template Conservation |   |
  |   |   |   |   |   |   | . |   |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   | . | . | . | . | . | . | . | . |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|   |
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |
| Template Sequence |   |
H | S | D | W | Q | I | P | . |
D | R | Y | E | I | R | H | L | H | V | C | E | A | Y | D | K | L | R | V | . |
. |
. |
. |
. |
. |
. |
. |
V | A | I | K | K | I | L | R | V | F | E | D | L | I | D | C | K | R | I | L | R | E | I | A | I | L | N | R | L | N | H | D | H | V | V | K | V | L | D | I | V | I | P | K | D |
| Template Known Secondary structure |   |
| S | S |
|
| S |
| . | T | T |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|  | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
| S | T | T | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| T | T | B |
|
|  |  |  |  |
|
|
| S |
|
| Template Predicted Secondary structure |   |
|
|
|  |  |  |
| . |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
46 | . | . | . | 50 | . | . | |
. | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . |
|   |
|   |   |
|
255 | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . |
| Predicted Secondary structure |   |
. |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
. |
S | V | G | D | P | V | Y | I | I | T | E | L | M | A | K | G | S | L | L | E | L | L | R | D | S | D | E | K | V | L | P | V | S | E | L | L | D | I | A | W | Q | V | A | E | G | M | C | Y | L | E | S | Q | N | Y | I | H | R | D | L | A | A | R | N | I | L | V | G | E | N | T | L | C | K | V | G | D | F | G | L |
| Query Conservation |   |
. |   |   |   |   |   |   |   |
|
|
|
|
|   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |   |
|   |   |   |   |   |
|
|   |
|
|   |   |   |
|
|
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
| Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |
|
|   |   |   |
|   |
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
| Template Sequence |   |
V | E | K | F | D | E | L | Y | V | V | L | E | I | A | D | S | D | F | K | K | L | F | R | T | P | V | Y | . |
. |
. |
L | T | E | L | H | I | K | T | L | L | Y | N | L | L | V | G | V | K | Y | V | H | S | A | G | I | L | H | R | D | L | K | P | A | N | C | L | V | N | Q | D | C | S | V | K | V | C | D | F | G | L |
| Template Known Secondary structure |   |
T | T | T |
|
|
|  |  |  |  |  |
|
|
| S |  |  |  |  |  |  |  |  | S | S |
|
| . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| B |
|
|
|
|
| G | G | G |  |  |  |
| T | T |
|
|  |  |  |
|
|
| T | T |
| Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
| . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
126 | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | |
|
|
. | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . |
|   |
|   |   |
334 | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | |
. | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
| Query Sequence |   |
A | R | L | I | K | E | D | V | Y | L | S | H | D | H | N | I | P | Y | K | W | T | A | P | E | A | L | S | R | G | H | . |
Y | S | T | K | S | D | V | W | S | F | G | I | L | L | H | E | M | F | S | R | G | Q | V | P | Y | P | G | M | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
| Query Conservation |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|   |   |   |   | . |   |
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |
|   |
|   |   |
|
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|   |   |
|   |
|
|
|   | . |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
| Template Sequence |   |
A | R | T | V | D | Y | P | E | N | G | N | S | Q | L | P | V | T | R | W | Y | R | A | P | E | L | I | L | L | Q | E | N | Y | T | E | A | I | D | V | W | S | I | G | C | I | F | A | E | L | L | N | . |
M | I | K | E | N | V | A | Y | H | A | D | R | G | P | L | F | P | T | R | G | N | R | D | Q | L | N | V | I | F |
| Template Known Secondary structure |   |
| B |
| T | T | S |
| T | T |
|
|
|
|
|
|
|
|
| T | T |
|
|  |  |  |  | T | T |
|
|
|
|
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | . | T | S | T | T | T |
| S | S | G | G | G |
|
|
| S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
203 | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | |
. | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . |
|   |
|   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
393 | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | |
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | H | E | A | F | L | R | V | D | A | G | Y | R | M | P | C | P | L | . |
. |
. |
. |
. |
. |
E | C | P | P | S | V | H | K | L | M | L | T | C | W | C | R | D | P | E | Q | R | P | C | F | K | A | L | R | E |
| Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |   |   |
|   |   |
|   |
|   |   |   |
|   | . | . | . | . | . | . |   |   |
|   |   |
|   |   |
|
|   |   |
|   |   |   |
|
|   |   |
|
|
|   |   |   |
|   |   |
| Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|   |   |
|
|   |   |
|
|   |   |
|
|
|
|   |
|   |
|   |
| Template Sequence |   |
N | I | L | G | T | P | S | E | E | D | I | E | A | L | E | K | E | D | A | K | R | Y | I | R | I | F | P | K | R | E | G | T | D | L | A | E | R | F | P | A | S | S | A | D | A | I | H | L | L | K | R | M | L | V | F | N | P | N | K | R | I | T | I | N | E | C | L | A |
| Template Known Secondary structure |   |
 |  |  |
|
|
|
|  |  |  |  |  | T | S | S |
|  |  |  |  |  |  |  | T | T | S |
|
|
|
|
|
|
| G | G | G | G | S | T | T | S |
|  |  |  |  |  |  |  |  |  |  | S |
| S | S | T | T | T | S |
|
|  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
329 | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . |
|   |