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Job DescriptionQ13882
Confidence100.00%DateWed May 9 17:41:40 BST 2012
Rank177Aligned Residues231
% Identity25%Templatec3o96A_
PDB info PDB header:transferaseChain: A: PDB Molecule:rac-alpha serine/threonine-protein kinase; PDBTitle: crystal structure of human akt1 with an allosteric inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   184.....190.........200.........210. ........220.........230.........240.........250.........260..
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Query Sequence  WERPREEFTLCRKLGSGYFGEVFEGLWK. DRVQVAIKVISRDNLLHQQMLQSEIQAMKKLRHKHILALYAVVSVGDPVYI
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Template Sequence  KQVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKE. . . . . . . VIVANRVLQNSRHPFLTALKYSFQTHDRLCF
Template Known Secondary structure  T


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   112.......120.........130.........140.........150... ......160.........170.........180....
 
   263......270.........280.........290.........300...... ...310.........320.........330.........340.
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Query Sequence  ITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEGMCYLESQ. NYIHRDLAARNILVGENTLCKVGDFGLARLIKEDV
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Template Sequence  VMEYANGGELFFHLSRE. . RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKE. . . . .
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   226...230.........240.. .......250.........260.........270.........280.........290........
 
   342.......350.........360.........370.........380.........390.........400.........410.........420.
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Query Sequence  YLSHDHNIPYKWTAPEALSRGHYSTKSDVWSFGILLHEMFSRGQVPYPGMSNHEAFLRVDAGYRMPCPLECPPSVHKLML
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Template Sequence  . . . . . . . . . PEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMC. GRLPFYNQDHEKLFELILMEE. IRFPRTLGPEAKSLLS
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   313......320.........330.........340.... .....350.........360..... ....370.........380.
 
   422.......430. ........
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Query Sequence  TCWCRDPEQR. . . . . PCFKALRE
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Template Sequence  GLLKKDPKQRLGGGSEDAKEIMQ
Template Known Secondary structure  T
SSTTTSTT
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   382.......390.........400....
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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