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Job DescriptionQ13882
Confidence100.00%DateWed May 9 17:41:40 BST 2012
Rank166Aligned Residues250
% Identity28%Templatec3mtfB_
PDB info PDB header:transferaseChain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor
Resolution2.15 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   189190.........200.........210.........220.........230.........240.........250... ......260....
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Query Sequence  EEFTLCRKLGSGYFGEVFEGLWKDRVQVAIKVISRDNLLHQQMLQSEIQAMKKLRHKHILALYAV. . . . VSVGDPVYIIT
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Template Sequence  RDITLLECVGKGRYGEVWRGSW. QGENVAVKIFSSRDEK. SWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLIT
Template Known Secondary structure  TTTT.TT
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   206...210.........220....... ..230.........240... ......250.........260.........270.........280...
 
   265....270.........280.........290.........300........ .310.........320.........330......
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Query Sequence  ELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEGMCYLESQNY. . . . . . . . IHRDLAARNILVGENTLCKVGDFGLARL
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Template Sequence  HYHEMGSLYDYLQLTTLD. . . TVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVM
Template Known Secondary structure 

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B

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STT
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SGGG
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   284.....290.........300. ........310.........320.........330.........340.........350.........360
 
   337 ..340.........350.........360... ......370.........380.........390...
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Query Sequence  I. . . . KEDVYLSHDHNIPYKWTAPEALSRGH. . . . . . YSTKSDVWSFGILLHEMFSRGQVPYPGMSN. . . . . . . . . . . . .
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Template Sequence  HSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVAR. RMVSNGIVEDYKPPFYDVVPNDP
Template Known Secondary structure  TTTT








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   361........370.........380.........390.........400.........410...... ...420.........430.........
 
   394.....400.........410. ........420.........430.........440....
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Query Sequence  . . HEAFLRVDAGYRMPCPLE. . . . . . CPPSVHKLMLTCWCRDPEQRPCFKALRERLSSF
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Template Sequence  SFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKI
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   440.........450.........460.........470.........480.........490........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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