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Job DescriptionQ13882
Confidence100.00%DateWed May 9 17:41:40 BST 2012
Rank70Aligned Residues251
% Identity35%Templatec3d4qA_
PDB info PDB header:transferaseChain: A: PDB Molecule:b-raf proto-oncogene serine/threonine-protein kinase; PDBTitle: pyrazole-based inhibitors of b-raf kinase
Resolution2.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   182.......190.........200.........210.........220.........230 .........240.........250.........
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Query Sequence  DDWERPREEFTLCRKLGSGYFGEVFEGLWKDRVQVAIKVISRDNLLHQQ. . MLQSEIQAMKKLRHKHILALYAVVSVGDP
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Template Sequence  DDWEIPDGQITVGQRIGSGSFGTVYKGKWHG. . DVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMG. YSTKPQ
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B

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   448.450.........460.........470........ .480.........490.........500.........510........ .520....
 
   260.........270.........280.........290.........300.........310.........320.........330.........
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Query Sequence  VYIITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEGMCYLESQNYIHRDLAARNILVGENTLCKVGDFGLARLIKE
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Template Sequence  LAIVTQWCEGSSLYHHLHII. ETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVLSG
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SS
BTS.




TT
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SGGGTTT


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   525....530.........540.... .....550.........560.........570.........580.........590.........600...
 
   340.........350.........360... ......370.........380.........390..... ....400....... ..410.
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Query Sequence  DVYLSHDHNIPYKWTAPEALSRGH. . . YSTKSDVWSFGILLHEMFSRGQVPYPGMSNHE. AFLRVDAGYRMP. . . . CPLE
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Template Sequence  . . . . . . . . . . SILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMT. GQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSN
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TT

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   616...620.........630.........640.........650. ........660.........670.........680....
 
   412.......420.........430.........440.......
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Query Sequence  CPPSVHKLMLTCWCRDPEQRPCFKALRERLSSFTSY
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Template Sequence  CPKAMKRLMAECLKKKRDERPLFPQILASIELLARS
Template Known Secondary structure  S
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SSGGGS

T
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   685....690.........700.........710.........720
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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