|   |   |
68 | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |
|
|
|  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
A | E | R | E | T | V | E | S | E | P | W | F | F | G | C | I | S | R | S | E | A | V | R | R | L | Q | A | E | G | N | A | T | G | A | F | L | I | R | V | S | E | K | P | S | A | D | Y | V | L | S | V | R | D | T | Q | A | V | R | H | Y | K | I | W | R | R | A | G | G | R | L | H | L | N | E | A | V | S | F | L | S |
| Query Conservation |   |
  |   |   |   |   |
|   |   |   |   |
|   |   |
|   |
|   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |
|   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |
|   | . | . | . | . |   |   |
|   |
|
|
|
|   |
|   |   |   | . | . | . |   |   |   |
|
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
| Template Sequence |   |
E | V | Q | K | P | L | H | E | Q | L | W | Y | H | G | A | I | P | R | A | E | V | A | E | L | L | V | . |
. |
. |
. |
H | S | G | D | F | L | V | R | E | S | Q | Q | E | . |
. |
. |
Y | V | L | S | V | P | R | H | F | I | I | N | L | Y | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | L | F | P | S |
| Template Known Secondary structure |   |
G | G | G | S |
| G | G | G |
| T | T | B |
| T | T |
|
|  |  |  |  |  |  |  |
|
| . | . | . | . | S | T | T |  |  |  |  |  |  |
|
|
|
| . | . | . |  |  |  |  |
|
|
|  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
| S |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  | . | . | . | . |  |
|
|
|  |  |  |  |  |
|
|
|  | . | . | . |  |  |  |  |  |  |
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | |
|
|
|
. | . | . | . | 480 | . | . | . | . | . | . | . | . | |
|
|
. | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . |
|   |
|   |   |
148 | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | |
. | . | . | . | . | . | . | . | 220 | . | |
. | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |  | . |
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| Query Sequence |   |
L | P | E | L | V | N | Y | H | R | A | Q | S | L | S | H | G | L | R | L | A | A | P | C | R | K | H | E | P | E | P | L | P | H | W | D | D | W | E | R | P | R | E | E | F | T | L | C | R | K | L | G | S | G | Y | F | G | E | V | F | E | G | L | W | K | . |
D | R | V | Q | V | A | I | K | V | I | . |
S | R | D | N |
| Query Conservation |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   | . |   |   |   |   |
|
|
|
|   |
| . |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| Template Conservation |   |
  |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |
| Template Sequence |   |
I | P | L | L | I | D | H | L | L | S | T | Q | Q | P | L | V | V | L | H | R | A | V | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | D | K | W | V | L | N | H | E | D | L | V | L | G | E | Q | I | G | R | G | N | F | G | E | V | F | S | G | R | L | R | A | D | N | T | L | V | A | V | K | S | C | R | E | T | L | P |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
|
|
|
|  |  |
|
| . | . | . | . | . | . | . | . | . | . |
|
| T | T | B |
|
| G | G | G |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |
|
| T | T | S |
|
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |
|  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
523 | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . |
|   |
|   |   |
226 | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | L | H | Q | Q | M | L | Q | S | E | I | Q | A | M | K | K | L | R | H | K | H | I | L | A | L | Y | A | V | V | S | V | G | D | P | V | Y | I | I | T | E | L | M | A | K | G | S | L | L | E | L | L | R | D | S | D | E | K | V | L | P | V | S | E | L | L | D | I | A | W | Q | V | A | E | G | M | C | Y | L | E | S |
| Query Conservation |   |
  |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|   |
|
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |
|   |
|   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
P | D | L | K | A | K | F | L | Q | E | A | R | I | L | K | Q | Y | S | H | P | N | I | V | R | L | I | G | V | C | T | Q | K | Q | P | I | Y | I | V | M | E | L | V | Q | G | G | D | F | L | T | F | L | R | T | E | G | A | R | . |
L | R | V | K | T | L | L | Q | M | V | G | D | A | A | A | G | M | E | Y | L | E | S |
| Template Known Secondary structure |   |
 |  |  |  | T | T | T | T |  |  |  |  |  |  | T | T |
|
|
| T | T | B |
|
|  |  |  |  |  |
| S | S | S | S |
|  |  |  |  |  |
|
| T | T |
| B |  |  |  |  |  |  |  |  | G | G | G | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
598 | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | |
. | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . |
|   |
|   |   |
306 | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | |
|
. | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . |
| Predicted Secondary structure |   |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  | . | . |
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Q | N | Y | I | H | R | D | L | A | A | R | N | I | L | V | G | E | N | T | L | C | K | V | G | D | F | G | L | A | R | L | I | K | E | D | V | Y | L | S | H | . |
. |
D | H | N | I | P | Y | K | W | T | A | P | E | A | L | S | R | G | H | Y | S | T | K | S | D | V | W | S | F | G | I | L | L | H | E | M | F | S | R |
| Query Conservation |   |
  |   |   |
|
|   |
|
|   |   |   |
|
|
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |
|   |
|
|
|   |
|   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|
|
|   |
|
|   |
|   |
| Template Sequence |   |
K | C | C | I | H | R | D | L | A | A | R | N | C | L | V | T | E | K | N | V | L | K | I | S | D | F | G | M | S | R | E | E | A | D | G | V | Y | A | A | S | G | G | L | R | Q | V | P | V | K | W | T | A | P | E | A | L | N | Y | G | R | Y | S | S | E | S | D | V | W | S | F | G | I | L | L | W | E | T | F | S | L |
| Template Known Secondary structure |   |
T | T |  |  |
| S |
|
| S | G | G | G |  |  |  |
| T | T |
|
|  |  |  |
|
| G | G | G |
|  |  |
| T | T | S |  |  |  |
|
| S | S |
|
|
|
|
| G | G | G | S |
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
677 | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . |
|   |
|   |   |
384 | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
G | Q | V | P | Y | P | G | M | S | N | H | E | A | F | L | R | V | D | A | G | Y | R | M | P | C | P | L | E | C | P | P | S | V | H | K | L | M | L | T | C | W | C | R | D | P | E | Q | R | P | C | F | K | A | L | R | E | R | L | S | S | F | T | S |
| Query Conservation |   |
|   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |
|
|   |   |
|   |   |   |
|
|   |   |
|
|
|   |   |   |
|   |   |   |
|   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |
|
|   |   |
|
|   |   |
|
|   |   |
|
|
|   |   |
|
|   |   |   |
|   |   |
|   |   |
| Template Sequence |   |
G | A | S | P | Y | P | N | L | S | N | Q | Q | T | R | E | F | V | E | K | G | G | R | L | P | C | P | E | L | C | P | D | A | V | F | R | L | M | E | Q | C | W | A | Y | E | P | G | Q | R | P | S | F | S | T | I | Y | Q | E | L | Q | S | I | R | K |
| Template Known Secondary structure |   |
S |
|
| S | S | T | T | S |
|  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  | T |
| S | S | G | G | G | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
757 | . | . | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . | . | . | . | . | 780 | . | . | . | . | . | . | . | . | . | 790 | . | . | . | . | . | . | . | . | . | 800 | . | . | . | . | . | . | . | . | . | 810 | . | . | . | . | . | . | . | . | . |
|   |