|   |   |
189 | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | E | F | T | L | C | R | K | L | G | S | G | Y | F | G | E | V | F | E | G | L | W | K | D | R | V | Q | V | A | I | K | V | I | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | D | N | L | L | H | Q | Q | M | L | Q | S | E | I | Q | A | M | K | K | L | R | H | K | H | I | L | A | L | Y |
| Query Conservation |   |
  |   |   |   |
|   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|   |
|
|
|
|
|   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|   |
|   |   |   |
|
|   |
|   |
|
|   |
|
|   |   |   |   |   |   | . |   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|   |
|   |   |
|
|   |   |   |
| Template Sequence |   |
N | D | Y | R | I | I | R | T | L | N | Q | G | K | F | N | K | I | I | L | C | E | K | D | N | . |
K | F | Y | A | L | K | K | Y | E | K | S | L | L | E | K | K | R | D | F | T | K | S | N | N | D | K | I | S | I | K | S | K | Y | D | D | F | K | N | E | L | Q | I | I | T | D | I | K | N | E | Y | C | L | T | C | E |
| Template Known Secondary structure |   |
T | T |  |  |  |  |  |  |  |  |  |
| S | S |
|  |  |  |  |  |  |  | T | T | . |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |
|
|
| S | S | S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| S | S | B |
|
|
| S |
| Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
| . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
26 | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | |
50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . |
|   |
|   |   |
252 | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | |
|
|
|
|
|
. | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | |
. | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  | . | . | . | . | . | . |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
A | V | V | S | V | G | D | P | V | Y | I | I | T | E | L | M | A | K | G | S | L | L | E | L | L | . |
. |
. |
. |
. |
. |
R | D | S | D | E | K | V | L | P | V | S | E | L | L | D | I | A | W | Q | V | A | E | G | M | C | Y | L | E | . |
S | Q | N | Y | I | H | R | D | L | A | A | R | N | I | L | V | G | E | N | T |
| Query Conservation |   |
|   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |   |
|
|
|   |   |   |
| . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |   |
|   | . |   |   |   |   |
|
|   |
|
|   |   |   |
|
|
|   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
G | I | I | T | N | Y | D | E | V | Y | I | I | Y | E | Y | M | E | N | D | S | I | L | K | F | D | E | Y | F | F | V | L | D | K | N | Y | T | C | F | I | P | I | Q | V | I | K | C | I | I | K | S | V | L | N | S | F | S | Y | I | H | N | E | K | N | I | C | H | R | D | V | K | P | S | N | I | L | M | D | K | N | G |
| Template Known Secondary structure |   |
 |  |  |  | S | S | S |  |  |  |  |  |  |  |
|
| T | T |
| B | S | S |  |  | S | S | S |  |  | S | S |
| S | S | S |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |
| S |
|
|
| G | G | G |  |  |  |
| S | S |
|
| Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
105 | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . |
|   |
|   |   |
325 | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | |
. | . | . | . | . | . | . | . | 400 | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . |
|  |  |  |  |  |  |  |  |  |
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | C | K | V | G | D | F | G | L | A | R | L | I | K | E | D | V | Y | L | S | H | D | H | N | I | P | Y | K | W | T | A | P | E | A | L | S | R | G | H | Y | S | T | K | S | D | V | W | S | F | G | I | L | L | H | E | M | F | S | R | G | Q | V | P | Y | P | G | M | . |
S | N | H | E | A | F | L | R | V | D | A | G |
| Query Conservation |   |
  |   |
|
|   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |
|   |
|   |   |
|
|   |   |   | . |   |   |   |   |
|   |   |   |
|   |   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |
|
|   |
|
|
|   | . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
| Template Sequence |   |
R | V | K | L | S | D | F | G | E | S | E | Y | M | V | D | K | K | I | K | G | S | R | G | T | Y | E | F | M | P | P | E | F | F | S | N | E | S | S | Y | N | G | A | K | V | D | I | W | S | L | G | I | C | L | Y | V | M | F | Y | . |
N | V | V | P | F | S | L | K | I | S | L | V | E | L | F | N | N | I | R | T | K |
| Template Known Secondary structure |   |
|  |  |  |
|
|
| T | T |
|  |  |
| B | T | T |  |  |  |
| S |
| S |
| G | G | G |
|
| G | G | G | G | S | S |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| S | S |
|
| S | S | S |  |  |  |  |  |  |  | T | T | T |
|
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
185 | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | |
. | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . |
|   |
|   |   |
404 | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Y | R | M | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | C | P | L | E | C | P | P | S | V | H | K | L | M | L | T | C | W | C | R | D | P | E | Q | R | P | C | F | K | A | L | R | E |
| Query Conservation |   |
  |
|   | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |   |
|   |   |
|   |   |
|
|   |   |
|   |   |   |
|
|   |   |
|
|
|   |   |   |
|   |   |
| Alig confidence |   |
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |
|
|   |   |
|
|
|   |   |
|
|
|   |
| Template Sequence |   |
N | I | E | Y | P | L | D | R | N | H | F | L | Y | P | L | T | N | F | L | S | N | E | D | I | D | F | L | K | L | F | L | R | K | N | P | A | E | R | I | T | S | E | D | A | L | K |
| Template Known Secondary structure |   |
|
|
|
|
|
| G | G | G | T | T | S | T | T | T |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | S |
| S | S | T | T | T | S |
|
|  |  |  |  |  | T |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
264 | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . |
|   |