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Job DescriptionQ13882
Confidence100.00%DateWed May 9 17:41:40 BST 2012
Rank7Aligned Residues365
% Identity36%Templatec2ozoA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: autoinhibited intact human zap-70
Resolution2.60 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   70.........80.........90.........100.........110.........120.........130.........140.........
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Query Sequence  RETVESEPWFFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSVRDTQAVRHYKIWRRAGGRLHLNEAVSFLSLP
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Template Conservation 
       
 

 


  

  
   
  

 



 
    
   

      
 
  
         
     
 

 
Template Sequence  PDPAAHLPFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVRFHHFPIERQLNGTYAIAGGKAHCGPA
Template Known Secondary structure 

TTSS
TTB
BS

TTT

TT
TTBTT
TT
TTS
TTS

BSS
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   2.......10.........20.........30.........40.........50.........60.........70.........80.
 
   150.........160.........170.........180.....
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Query Sequence  ELVNYHRAQSLSHGLRLAAPCRKHEPEPLPHWDDWE. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  ELCEFYSRDPDGLPCNLRKPCNRPSGLEPQPGVFDCLRDAMVRDYVRQTWKLEGEALEQAIISQAPQVEKLIATTAHERM
Template Known Secondary structure  TS

TTSSS


SB



TT


B




TTS
TTTS
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   82.......90.........100.........110.........120.........130.........140.........150.........160.
 
  
Predicted Secondary structure  ................................................................................
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
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Template Sequence  PWYHSSLTREEAERKLYSGAQTDGKFLLRPRKEQGTYALSLIYGKTVYHYLISQDKAGKYCIPEGTKFDTLWQLVEYLKL
Template Known Secondary structure  TTB
TT

SSS


TT

SSTTTT
TT


TTS
SS
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   162.......170.........180.........190.........200.........210.........220.........230.........240.
 
   186...190.........200.........210.... .....220....
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . RPREEFTLCRKLGSGYFGEVFEGLWKDRV. . . QVAIKVISRD
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Template Sequence  KADGLIYCLKEACPNMDTSVFESPFSDPEELKDKKLFLKRDNLLIADIELGCGNFGSVRQGVYRMRKKQIDVAIKVLKQG
Template Known Secondary structure 

TT
SS


SB






S
SSSSS
S
SS



SB

TTS
SSS
SS




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   242.......250.........260.........270.........280.........290.........300.........310.........320.
 
   225... .230.........240.........250.........260.........270.........280.........290.........300...
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Query Sequence  NLLH. QQMLQSEIQAMKKLRHKHILALYAVVSVGDPVYIITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEGMCYL
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Template Sequence  TEKADTEEMMREAQIMHQLDNPYIVRLIGVC. QAEALMLVMEMAGGGPLHKFLVGKREE. IPVSNVAELLHQVSMGMKYL
Template Known Secondary structure 
SSTTTT


TTB

.SSS

TT
BTT
TTT.S
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   375....380.........390.........400..... ....410.........420.........430.. .......440.........450..
 
   304.....310.........320.........330.........340.........350.........360.........370.........380...
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Query Sequence  ESQNYIHRDLAARNILVGENTLCKVGDFGLARLIKEDVYLSHDHNIPYKWTAPEALSRGHYSTKSDVWSFGILLHEMFSR
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Template Sequence  EEKNFVHRNLAARNVLLVNRHYAKISDFGLSKALG. . . . . . . . . . . PLKWYAPECINFRKFSSRSDVWSYGVTMWEALSY
Template Known Secondary structure  TT


S

SGGGTT


STTTT

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TTS




TT
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   453......460.........470.........480....... ..490.........500.........510.........520.
 
   384.....390.........400.........410.........420.........430.........440.......
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Query Sequence  GQVPYPGMSNHEAFLRVDAGYRMPCPLECPPSVHKLMLTCWCRDPEQRPCFKALRERLSSFTSY
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Template Conservation 
  
            
        
   
     

  
    
  

    
   
      
Template Sequence  GQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYALMSDCWIYKWEDRPDFLTVEQRMRACYYS
Template Known Secondary structure  S

TTTT

STT





TT

TT
SSTTTS

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   536...540.........550.........560.........570.........580.........590.........
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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