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Job DescriptionQ13882
Confidence100.00%DateWed May 9 17:41:40 BST 2012
Rank57Aligned Residues251
% Identity24%Templatec2j51A_
PDB info PDB header:transferaseChain: A: PDB Molecule:ste20-like serine/threonine-protein kinase; PDBTitle: crystal structure of human ste20-like kinase bound to 5-2 amino-3-((4-(aminosulfonyl)phenyl)amino)-n-(2,6-3 difluorophenyl)-1h-1,2,4-triazole-1-carbothioamide
Resolution2.1 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   187..190.........200.........210. ........220.........230.........240.........250.........260.....
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Query Sequence  PREEFTLCRKLGSGYFGEVFEGLWK. DRVQVAIKVISRDNLLHQQMLQSEIQAMKKLRHKHILALYAVVSVGDPVYIITE
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Template Sequence  PEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIE
Template Known Secondary structure  GGGTTTTTT


SSSTT


TTB

TT
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   30.........40.........50.........60.........70.........80.........90.........100.........
 
   266...270.........280.........290.........300.........310.........320.........330.........340.....
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Query Sequence  LMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEGMCYLESQNYIHRDLAARNILVGENTLCKVGDFGLARLIKEDVYLSH
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Template Sequence  FCAGGAVDAVMLELERP. LTESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRD
Template Known Secondary structure 

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SGGG
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   110.........120...... ...130.........140.........150.........160.........170.........180........
 
   346...350......... 360.........370.........380.........390.........400.... .....410........
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Query Sequence  DHNIPYKWTAPEAL. . . . . SRGHYSTKSDVWSFGILLHEMFSRGQVPYPGMSNHEAFLRVDAGY. . RMPCPLECPPSVHK
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Template Sequence  SFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAE. IEPPHHELNPMRVLLKIAKSEPPTLAQPSRWSSNFKD
Template Known Secondary structure 


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TT

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   189190.........200.........210.........220.........230 .........240.........250.........260.......
 
   419420.........430.........
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Query Sequence  LMLTCWCRDPEQRPCFKALRE
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Template Sequence  FLKKCLEKNVDARWTTSQLLQ
Template Known Secondary structure  S
SSTTTS

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   268.270.........280........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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