|   |   |
188 | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | |
. | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | |
|
|
|
|
|
. | . | . | . | 260 |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |  |
|
|  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
| Query Sequence |   |
R | E | E | F | T | L | C | R | K | L | G | S | G | Y | F | G | E | V | F | E | G | L | W | K | . |
D | R | V | Q | V | A | I | K | V | I | S | R | D | N | L | L | H | Q | Q | M | L | Q | S | E | I | Q | A | M | K | K | L | R | H | K | H | I | L | A | L | Y | A | V | V | S | . |
. |
. |
. |
. |
. |
V | G | D | P | V |
| Query Conservation |   |
  |   |   |   |   |
|   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   | . |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|   |
|
|
|
|
|   |
|   |
|   |   |   | . | . | . | . | . | . |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
| Template Conservation |   |
  |   |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |
|
|
|
|   |
|   | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
A | S | D | F | E | E | I | A | V | L | G | Q | G | A | F | G | Q | V | V | K | A | R | N | A | L | D | S | R | Y | Y | A | I | K | K | I | R | . |
H | T | E | E | K | L | S | T | I | L | S | E | V | M | L | L | A | S | L | N | H | Q | Y | V | V | R | Y | Y | A | A | W | L | E | R | R | N | F | V | K | K | S | T | L |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |  |  | . |  |
|  |  |  |  | T | T | T |  |  |  |  |  |  |  | T | T |
|
|
| T | T | B |
|
|  |  |  |  |  |  |  |
|
| T | T |
|
|
|  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
596 | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | |
. | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . |
|   |
|   |   |
261 | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 |
| Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Y | I | I | T | E | L | M | A | K | G | S | L | L | E | L | L | R | D | S | D | E | K | V | L | P | V | S | E | L | L | D | I | A | W | Q | V | A | E | G | M | C | Y | L | E | S | Q | N | Y | I | H | R | D | L | A | A | R | N | I | L | V | G | E | N | T | L | C | K | V | G | D | F | G | L | A | R | L | I | K | E | D |
| Query Conservation |   |
  |
|
|
|
|
|   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |   |
|   |   |   |   |   |
|
|   |
|
|   |   |   |
|
|
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|
|   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
| Template Conservation |   |
  |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . | . | . | . | . | . | . |
| Template Sequence |   |
F | I | Q | M | E | Y | C | E | N | G | T | L | Y | D | L | I | H | S | E | N | L | N | . |
Q | Q | R | D | E | Y | W | R | L | F | R | Q | I | L | E | A | L | S | Y | I | H | S | Q | G | I | I | H | R | D | L | K | P | M | N | I | F | I | D | E | S | R | N | V | K | I | G | D | F | G | L | . |
. |
. |
. |
. |
. |
. |
| Template Known Secondary structure |   |
 |  |  |  |  |
|
|
| S |
| B |  |  |  |  |  |  |  | S |
| T | T | . | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| S |
|
|
| G | G | G |  |  |  |
| T | T | S |
|  |  |  |
| S |
|
|
| . | . | . | . | . | . | . |
| Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
| . | . | . | . | . | . | . |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
785 | . | . | . | . | 790 | . | . | . | . | . | . | . | . | . | 800 | . | . | . | . | . | . | |
. | . | . | 810 | . | . | . | . | . | . | . | . | . | 820 | . | . | . | . | . | . | . | . | . | 830 | . | . | . | . | . | . | . | . | . | 840 | . | . | . | . | . | . | . | . | . | 850 | . | . | . | . | . | . | |
|
|
|
|
|
|
|   |
|   |   |
341 | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | |
|
|
. | . | . | . | . | 410 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|  |  |  |
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
V | Y | L | S | H | D | H | N | I | P | Y | K | W | T | A | P | E | A | L | S | R | G | H | Y | S | T | K | S | D | V | W | S | F | G | I | L | L | H | E | M | F | S | R | G | Q | V | P | Y | P | G | M | S | N | H | E | A | F | L | R | V | D | A | G | Y | . |
. |
. |
R | M | P | C | P | L | E | C | P | P | S | V | H |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |
|   |
|   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   | . | . | . |
|   |   |   |
|   |   |   |
|   |   |
|   |
| Alig confidence |   |
. | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
. | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   | . | . | . |   |   |   |   |   |   |   |
|
|
|
|
|
|   |
|
|
|
|
|
|   | . |
| . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
| Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
G | T | A | M | Y | V | A | T | E | V | . |
. |
. |
L | H | Y | N | E | K | I | D | M | Y | S | L | G | I | I | F | F | E | M | I | Y | . |
P | . |
. |
F | S | T | G | M | E | R | V | N | I | L | K | K | L | R | S | V | S | I | E | F | P | P | D | F | D | D | N | K | M | K | V | E | K |
| Template Known Secondary structure |   |
. | . | . | . | . | . | . | . |
|
| G | G | G |
|
| T | T | T | . | . | . |
|
|
|
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | . |
| . | . |
| S | S |  |  |  |  |  |  |  |  |  |  |  | T | S | T | T |
|
|
|
| T | T | S |
| T | T | T | T |  |  |  |  |
| Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  | . | . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| . |
| . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|
|
|
|
|
|
886 | . | . | . | 890 | . | . | . | . | . | |
|
|
. | . | . | . | 900 | . | . | . | . | . | . | . | . | . | 910 | . | . | . | . | . | . | |
. | |
|
. | . | 920 | . | . | . | . | . | . | . | . | . | 930 | . | . | . | . | . | . | . | . | . | 940 | . | . | . | . | . | . | . | . | . | 950 | . |
|   |
|   |   |
418 | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
K | L | M | L | T | C | W | C | R | D | P | E | Q | R | P | C | F | K | A | L | R | E |
| Query Conservation |   |
  |
|
|   |   |
|   |   |   |
|
|   |   |
|
|
|   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|
|   |   |   |
|   |   |
|
|   |   |
|
|
|   |   |
|
|
|   |
| Template Sequence |   |
K | I | I | R | L | L | I | D | H | D | P | N | K | R | P | G | A | R | T | L | L | N |
| Template Known Secondary structure |   |
 |  |  |  |  |  | T |
| S |
| G | G | G | S |
|
|  |  |  |  |  | T |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
956 | . | . | . | 960 | . | . | . | . | . | . | . | . | . | 970 | . | . | . | . | . | . | . |
|   |