Job Description Q13882 Confidence 100.00% Date Wed May 9 17:41:40 BST 2012 Rank 85 Aligned Residues 251 % Identity 35% Template c1xkkA_ PDB info PDB header:transferase Chain: A: PDB Molecule:epidermal growth factor receptor; PDBTitle: egfr kinase domain complexed with a quinazoline inhibitor-2 gw572016 Resolution 2.40 Å

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		186	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.		.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.
Predicted Secondary structure																												.
Query SS confidence																												.
Query Sequence		R	P	R	E	E	F	T	L	C	R	K	L	G	S	G	Y	F	G	E	V	F	E	G	L	W	K	.	D	R	V	Q	V	A	I	K	V	I	S	R	D	N	L	L	H	Q	Q	M	L	Q	S	E	I	Q	A	M	K	K	L	R	H	K	H	I	L	A	L	Y	A	V	V	S	V	G	D	P	V	Y	I	I	T
Query Conservation																												.
Alig confidence																												.													.	.	.																																	.
Template Conservation																																									.	.	.																																	.
Template Sequence		L	K	E	T	E	F	K	K	I	K	V	L	G	S	G	A	F	G	T	V	Y	K	G	L	W	I	P	V	K	I	P	V	A	I	K	E	L	R	E	.	.	.	K	A	N	K	E	I	L	D	E	A	Y	V	M	A	S	V	D	N	P	H	V	C	R	L	L	G	I	C	L	T	S	T	.	V	Q	L	I	T
Template Known Secondary structure				T	T	T											S	S																							.	.	.		T																	T	T	B									S	S	S	.
Template Predicted Secondary structure																																									.	.	.																																	.
Template SS confidence
		707	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.				.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.		.	.	780	.	.
		265	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	L	M	A	K	G	S	L	L	E	L	L	R	D	S	D	E	K	V	L	P	V	S	E	L	L	D	I	A	W	Q	V	A	E	G	M	C	Y	L	E	S	Q	N	Y	I	H	R	D	L	A	A	R	N	I	L	V	G	E	N	T	L	C	K	V	G	D	F	G	L	A	R	L	I	K	E	D	V	Y	L	S
Query Conservation
Alig confidence																				.																																																										.	.	.	.
Template Conservation																				.																																																										.	.	.	.
Template Sequence		Q	L	M	P	F	G	C	L	L	D	Y	V	R	E	H	K	D	N	.	I	G	S	Q	Y	L	L	N	W	C	V	Q	I	A	K	G	M	N	Y	L	E	D	R	R	L	V	H	R	D	L	A	A	R	N	V	L	V	K	T	P	Q	H	V	K	I	T	D	F	G	L	A	K	L	L	G	A	E	.	.	.	.
Template Known Secondary structure					T	T		B								T	S	S	S	.																							T	T				S				G	G	G						T	T								S					T	T	T	T	.	.	.	.
Template Predicted Secondary structure																				.																																																										.	.	.	.
Template SS confidence
		791	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.		.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.
		345	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		H	D	H	N	I	P	Y	K	W	T	A	P	E	A	L	S	R	G	H	Y	S	T	K	S	D	V	W	S	F	G	I	L	L	H	E	M	F	S	R	G	Q	V	P	Y	P	G	M	S	N	H	E	A	F	L	R	V	D	A	G	Y	R	M	P	C	P	L	E	C	P	P	S	V	H	K	L	M	L	T	C	W
Query Conservation
Alig confidence		.	.
Template Conservation		.	.
Template Sequence		.	.	E	K	V	P	I	K	W	M	A	L	E	S	I	L	H	R	I	Y	T	H	Q	S	D	V	W	S	Y	G	V	T	V	W	E	L	M	T	F	G	S	K	P	Y	D	G	I	P	A	S	E	I	S	S	I	L	E	K	G	E	R	L	P	Q	P	P	I	C	T	I	D	V	Y	M	I	M	V	K	C	W
Template Known Secondary structure		.	.					T	T	T	S																												T	T	S			T	T	T	T	S		G	G	G								T							T	T	B												T
Template Predicted Secondary structure		.	.
Template SS confidence
				866	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.
		425	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		C	R	D	P	E	Q	R	P	C	F	K	A	L	R	E	R	L	S	S	F	T	S	Y
Query Conservation
Alig confidence
Template Conservation
Template Sequence		M	I	D	A	D	S	R	P	K	F	R	E	L	I	I	E	F	S	K	M	A	R	D
Template Known Secondary structure			S	S	G	G	G	S																S
Template Predicted Secondary structure
Template SS confidence
		952	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions