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Job DescriptionQ08881
Confidence100.00%DateTue Apr 3 14:36:05 BST 2012
Rank86Aligned Residues333
% Identity25%Templatec3o96A_
PDB info PDB header:transferaseChain: A: PDB Molecule:rac-alpha serine/threonine-protein kinase; PDBTitle: crystal structure of human akt1 with an allosteric inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   2.......10.........20.........30.........40.........50.........60.........70.........80.
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Query Sequence  NNFILLEEQLIKKSQQKRRTSPSNFKVRFFVLTKASLAYFEDRHGKKRTLKGSIELSRIKCVEIVKSDISIPCHYKYPFQ
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Template Sequence  DVAIVKEGWLHKRGEYIKT. . . . . WRPRYFLLKNDGTFIGYKERPQDVEA. . PLNNFSVAQCQLMKTER. . . . PRPNTFI
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SSS

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GGGB
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B
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   3......10.........20. ........30.........40....... ..50.........60.... .....70.
 
   82.......90.. .......100.........110.........120.........130.........140.........150.........160
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Query Sequence  VVHDNYLLYVF. APDRESRQRWVLALKEETRNNNSLVPKYHPNFWMDGKWRCCSQLEKLATGCAQYDPTKNASKKPLPPT
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Template Sequence  IRCLQWTTVIERTFTPEEREEWTTAIQ. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  TT

TTGGGT.....................................................
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   75....80.........90.........100.
 
   161........170.........180.........190.........200.........210.........220.........230.........240
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Query Sequence  PEDNRRPLWEPEETVVIALYDYQTNDPQELALRRNEEYCLLDSSEIHWWRVQDRNGHEGYVPSSYLVEKSPNNLETYEWY
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   241........250.........260.........270.........280.........290.........300.........310.........320
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Query Sequence  NKSISRDKAEKLLLDTGKEGAFMVRDSRTAGTYTVSVFTKAVVSENNPCIKHYHIKETNDNPKRYYVAEKYVFDSIPLLI
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Template Sequence  . . . . . . . TVADGLK. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   105....110.
 
   321........330.........340.........350.........360.........370.........380.... .....390.........
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Query Sequence  NYHQHNGGGLVTRLRYPVCFGRQKAPVTAGLRYGKWVIDPSELTFVQEIGSGQFGLVHLGYWLN. KDKVAIKTIREGAMS
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . KQVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILK. . . . .
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TTSTTTTT

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   112.......120.........130.........140.........150.
 
   400.........410.........420.........430.........440.........450.........460.........470..... ...
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Query Sequence  EEDFIEEAEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYLEE. ACV
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Template Sequence  . KEVIVANRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERV. FSEDRARFYGAEIVSALDYLHSEKNV
Template Known Secondary structure  .GGGS



GGGTS

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   183......190.........200.........210.........220.........230.... .....240.........250.........260
 
   479480.........490.........500.........510.........520.........530.........540.........550........
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Query Sequence  IHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIP
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Template Sequence  VYRDLKLENLMLDKDGHIKITDFGLCKEPE. . . . . . . . . . . . . . . YLAPEVLEDNDYGRAVDWWGLGVVMYEMMC. GRLP
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   271........280.........290.........300 .........310.........320.........330 ....
 
   559560.........570.........580.........590.........600.. .......610
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Query Sequence  YENRSNSEVVEDISTGFRLYKPRLASTHVYQIMNHCWKERPEDR. . . . . PAFSRLLR
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Template Sequence  FYNQDHEKLFELILMEE. IRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQ
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TT

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   349350.........360..... ....370.........380.........390.........400....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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