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Job DescriptionQ08881
Confidence100.00%DateTue Apr 3 14:36:05 BST 2012
Rank164Aligned Residues251
% Identity22%Templatec3mtfB_
PDB info PDB header:transferaseChain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor
Resolution2.15 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   361........370.........380.........390.........400.........410.........420.... .....430......
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Query Sequence  SELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIREGAMSEEDFIEEAEVMMKLSHPKLVQLYGV. . . . CLEQAPICLVFE
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Template Sequence  RDITLLECVGKGRYGEVWRGSW. QGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITH
Template Known Secondary structure  TTTT.TT
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   206...210.........220....... ..230.........240.........250.........260.........270.........280....
 
   437..440.........450.........460.........470........ .480.........490.........500........
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Query Sequence  FMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYLEEACV. . . . . . . . IHRDLAARNCLVGENQVIKVSDFGMTRFVL
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Template Sequence  YHEMGSLYDYLQLTT. . LDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHS
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B

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B
STT
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SGGG
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   285....290......... 300.........310.........320.........330.........340.........350.........360..
 
   509510.........520.........530.... .....540.........550.........560....
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Query Sequence  . . . DDQYTSSTGTKFPVKWASPEVFSFSR. . . . . . YSSKSDVWSFGVLMWEVFSEGKIPYENRSN. . . . . . . . . . . . . . .
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Template Sequence  QSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVAR. RMVSNGIVEDYKPPFYDVVPNDPSF
Template Known Secondary structure  TTTT








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   363......370.........380.........390.........400.........410...... ...420.........430.........440.
 
   565....570.........580.. .......590.........600.........610.....
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Query Sequence  SEVVEDISTGFRLYKPRL. . . . . . ASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEI
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Template Sequence  EDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKI
Template Known Secondary structure  TTS






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   442.......450.........460.........470.........480.........490........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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