Return to main results Retrieve Phyre Job Id

Job DescriptionQ08881
Confidence100.00%DateTue Apr 3 14:36:05 BST 2012
Rank77Aligned Residues242
% Identity58%Templatec3k54A_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases.
Resolution1.94 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   353......360.........370.........380.........390.........400.........410.........420.........430..
Predicted Secondary structure 























Query SS confidence 















































































Query Sequence  YGKWVIDPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIREGAMSEEDFIEEAEVMMKLSHPKLVQLYGVCLEQAPIC
Query Conservation     


          

 
 

 
  
       



           
  
   
  
 
 


 
 
         
Alig confidence 










































.......





























Template Conservation       
          

 
 

 
 
        



 

 .......   

  
  
 




             
Template Sequence  YGSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKE. . . . . . . FIEEAKVMMNLSHEKLVQLYGVCTKQRPIF
Template Known Secondary structure 
GGGB

GGGSTTSS
TTT


.......
TT


TTB


SSSS
Template Predicted Secondary structure 










.......
















Template SS confidence 















































































   392.......400.........410.........420.........430.... .....440.........450.........460....
 
   433......440.........450.........460.........470.........480.........490.........500.........510..
Predicted Secondary structure 




































Query SS confidence 















































































Query Sequence  LVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQY
Query Conservation 

 
    


   
      
       
  


 

 


   





   



      

 





       
Alig confidence 








































































.......
Template Conservation   
        
                                                      
 
     .......
Template Sequence  IITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGFPV. . . . . . .
Template Known Secondary structure 

TT
GGG


TT


S

SGGG
TT







G.......
Template Predicted Secondary structure 










































.......
Template SS confidence 















































































   472.......480.........490.........500.........510.........520.........530.........540....
 
   513......520.........530.........540.........550.........560.........570.........580.........590..
Predicted Secondary structure 


































Query SS confidence 















































































Query Sequence  TSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASTHVYQIMN
Query Conservation               


 
     
 










 

 
 
  
            
  
     
      
  

 
Alig confidence  ..........





































































Template Conservation  ..........                 

 
 
    

 
                 
            
     

 
Template Sequence  . . . . . . . . . . RWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMY
Template Known Secondary structure  ..........GG





TTS

TTTTS
TT





TTS
Template Predicted Secondary structure  ..........










































Template SS confidence 















































































   562.......570.........580.........590.........600.........610.........620.........630.
 
   593......600.........610........
Predicted Secondary structure 






Query SS confidence 

























Query Sequence  HCWKERPEDRPAFSRLLRQLAEIAES
Query Conservation   
   

  


   
   
  
  
Alig confidence 

























Template Conservation   

  

  


  


  
  

  
Template Sequence  SCWHEKADERPTFKILLSNILDVMDE
Template Known Secondary structure  TT
SSGGGS

Template Predicted Secondary structure 







Template SS confidence 

























   632.......640.........650.......
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions