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Job DescriptionQ08881
Confidence100.00%DateTue Apr 3 14:36:05 BST 2012
Rank52Aligned Residues262
% Identity32%Templatec3fupB_
PDB info PDB header:transferaseChain: B: PDB Molecule:tyrosine-protein kinase jak2; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   354.....360.........370.........380.... .....390.... .....400.........410.........420.......
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Query Sequence  GKWVIDPSELTFVQEIGSGQFGLVHLGYWLN. . . . . KDKVAIKTIR. EGAMSEEDFIEEAEVMMKLSHPKLVQLYGVCLE
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Template Sequence  DPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCY.
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   840.........850.........860.........870.........880.........890.........900.........910........
 
   428.430.........440.........450.........460.........470.........480.........490.........500.......
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Query Sequence  QAPICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRFV
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Template Sequence  . SNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVL
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   919920.........930.........940.........950.........960.........970.........980.........990.......
 
   508.510.........520.........530.........540.........550.........560. ........570.
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Query Sequence  LDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYEN. . . . . . . . . . . . . . . . RSNSEVVEDI
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Template Sequence  PQDKEKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFT. YIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELL
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   1002.......1010.........1020.........1030.........1040....... ..1050.........1060.........1070.........1080
 
   572.......580.........590.........600.........610........
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Query Sequence  STGFRLYKPRLASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEIAES
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Template Sequence  KNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDQ
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   1083......1090.........1100.........1110.........1120.........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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