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Job DescriptionQ08881
Confidence100.00%DateTue Apr 3 14:36:05 BST 2012
Rank61Aligned Residues250
% Identity29%Templatec3d4qA_
PDB info PDB header:transferaseChain: A: PDB Molecule:b-raf proto-oncogene serine/threonine-protein kinase; PDBTitle: pyrazole-based inhibitors of b-raf kinase
Resolution2.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   354.....360.........370.........380.........390.........400. ........410.........420.........430
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Query Sequence  GKWVIDPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIREGAMSEE. . . DFIEEAEVMMKLSHPKLVQLYGVCLEQAP
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Template Sequence  DDWEIPDGQITVGQRIGSGSFGTVYKGKWHGD. . VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMG. YSTKPQ
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B

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   448.450.........460.........470......... 480.........490.........500.........510........ .520....
 
   431........440.........450.........460.........470.........480.........490.........500.........510
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Query Sequence  ICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDD
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Template Sequence  LAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVLSG.
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SS
BTS




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SGGGTTT


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   525....530.........540.........550.........560.........570.........580.........590.........600...
 
   511........520.........530.... .....540.........550.........560...... ...570........ .580..
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Query Sequence  QYTSSTGTKFPVKWASPEVFSFSR. . . YSSKSDVWSFGVLMWEVFSEGKIPYENRSNSE. VVEDISTGFRLY. . . . KPRL
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Template Sequence  . . . . . . . . . . SILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMT. GQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSN
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TT

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S.SS
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   616...620.........630.........640.........650. ........660.........670.........680....
 
   583......590.........600.........610........
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Query Sequence  ASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEIAES
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Template Sequence  CPKAMKRLMAECLKKKRDERPLFPQILASIELLARS
Template Known Secondary structure  S
T
SSGGGS

T
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   685....690.........700.........710.........720
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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