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Job DescriptionQ08881
Confidence100.00%DateTue Apr 3 14:36:05 BST 2012
Rank195Aligned Residues249
% Identity35%Templatec3c1xA_
PDB info PDB header:transferaseChain: A: PDB Molecule:hepatocyte growth factor receptor; PDBTitle: crystal structure of the tyrosine kinase domain of the2 hepatocyte growth factor receptor c-met in complex with a3 pyrrolotriazine based inhibitor
Resolution2.17 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   352.......360.. .......370.........380...... ...390.........400. ........410.........420...
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Query Sequence  RYGKWVIDPSE. . LTFVQEIGSGQFGLVHLGYWLNKD. . . . KVAIKTIREGAMSEE. . DFIEEAEVMMKLSHPKLVQLYG
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Template Sequence  AVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLG
Template Known Secondary structure  TTTTTB

STT

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   1065....1070.........1080.........1090.........1100.........1110.........1120.........1130.........1140....
 
   424.....430 .........440.........450.........460.........470.........480.........490.........500..
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Query Sequence  VCLEQAP. ICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFG
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Template Sequence  ICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKFLASKKFVHRDLAARNCMLDEKFTVKVADFL
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   1145....1150.........1160.........1170.........1180.........1190.........1200.........1210.........1220....
 
   503......510.........520.........530.........540.........550.........560.........570.........580..
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Query Sequence  MTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRL
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Template Sequence  PVK. . . . . . . . . . . . . . . . . . WMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEY
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   1246.. .1250.........1260.........1270.........1280.........1290.........1300.......
 
   583......590.........600.........610........
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Query Sequence  ASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEIAES
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Template Sequence  CPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFST
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SSGGGS

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   1308.1310.........1320.........1330.........1340...
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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