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Job DescriptionQ08881
Confidence100.00%DateTue Apr 3 14:36:05 BST 2012
Rank157Aligned Residues258
% Identity38%Templatec2yhvA_
PDB info PDB header:transferaseChain: A: PDB Molecule:alk tyrosine kinase receptor; PDBTitle: structure of l1196m mutant anaplastic lymphoma kinase
Resolution1.90 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   354.....360.........370.........380.........390.........400. ........410.........420.........430.
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Query Sequence  GKWVIDPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIREGAMSEE. . DFIEEAEVMMKLSHPKLVQLYGVCLEQAPI
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Template Sequence  DLKEVPRKNITL. . . IRGLAFGEVYEGQV. . PLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPR
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   1107..1110........ .1120.........1130.. .......1140.........1150.........1160.........1170.........1180.
 
   432.......440......... 450.........460.........470.........480.........490.........500.....
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Query Sequence  CLVFEFMEHGCLSDYLRT. . . . . . QRGLFAAETLLGMCLDVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTR
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Template Sequence  FILMELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDF.
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   1193......1200.........1210.........1220.........1230.........1240.........1250.........1260.........1270.
 
   506...510.........520.........530.........540.........550.........560.........570.........580.....
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Query Sequence  FVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLAST
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Template Sequence  . GMARDIYRGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPG
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   1272.......1280.........1290.........1300.........1310.........1320.........1330.........1340.........1350
 
   586...590.........600.........610........
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Query Sequence  HVYQIMNHCWKERPEDRPAFSRLLRQLAEIAES
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Template Sequence  PVYRIMTQCWQHQPEDRPNFAIILERIEYCTQD
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   1357..1360.........1370.........1380.........
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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