Job Description Q06124 Confidence 100.00% Date Wed May 9 17:40:46 BST 2012 Rank 18 Aligned Residues 293 % Identity 35% Template c2vexA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:tyrosine-protein phosphatase non-receptor type 1; PDBTitle: crystal strucutre of protein tyrosine phosphatase 1b in2 complex with an isothiazolidinone-containing inhibitor Resolution 2.20 Å

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		226	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	E	S	R	V	R	E	L	S	K	L	A	E	T	T	D	K	V	K	Q	G	F	W	E	E	F	E	T	L	Q	Q	Q	E	C	K	L	L	Y	S	R	K	E	G	Q	R	Q	E	N	K	N	K	N	R	Y	K	N	I	L	P	F	D	H	T	R	V	V	L	H	D	G	D	P	N	E	P	V	S	D	Y	I
Query Conservation
Alig confidence												.	.	.	.	.	.	.	.																		.	.																																			.	.	.	.	.
Template Conservation												.	.	.	.	.	.	.	.																		.	.																																			.	.	.	.	.
Template Sequence		M	E	K	E	F	E	Q	I	D	K	.	.	.	.	.	.	.	.	S	G	S	W	A	A	I	Y	Q	D	I	R	H	E	A	S	D	.	.	F	P	C	R	V	A	K	L	P	K	N	K	N	R	N	R	Y	R	D	V	S	P	F	D	H	S	R	I	K	L	H	Q	E	D	.	.	.	.	.	N	D	Y	I
Template Known Secondary structure												.	.	.	.	.	.	.	.		T													S			.	.				T	T	T	T	S	G	G	G	G	G	G		S	S	T	T					G	G	G					S		S	S	.	.	.	.	.
Template Predicted Secondary structure												.	.	.	.	.	.	.	.																		.	.																																			.	.	.	.	.
Template SS confidence
		3	.	.	.	.	.	.	10	.	.									.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.			30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.						.	.	.	.
		306	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.		.	.	.	.	.	380			.	.
Predicted Secondary structure																																																																							.							.	.
Query SS confidence																																																																							.							.	.
Query Sequence		N	A	N	I	I	M	P	E	F	E	T	K	C	N	N	S	K	P	K	K	S	Y	I	A	T	Q	G	C	L	Q	N	T	V	N	D	F	W	R	M	V	F	Q	E	N	S	R	V	I	V	M	T	T	K	E	V	E	R	G	K	S	K	C	V	K	Y	W	P	D	E	.	Y	A	L	K	E	Y	.	.	G	V
Query Conservation																																																																							.							.	.
Alig confidence												.	.	.	.	.	.	.	.																																																				.							.	.
Template Conservation												.	.	.	.	.	.	.	.
Template Sequence		N	A	S	L	I	K	M	E	E	A	.	.	.	.	.	.	.	.	Q	R	S	Y	I	L	T	Q	G	P	L	P	N	T	C	G	H	F	W	E	M	V	W	E	Q	K	S	R	G	V	V	M	L	N	R	V	M	E	K	G	S	L	K	C	A	Q	Y	W	P	Q	K	E	E	K	E	M	I	F	E	D	T	N
Template Known Secondary structure									T	T	T	.	.	.	.	.	.	.	.	T											T	T	T											T	T								S		S			T	T				S				S		S	S	T	T	S					G	G	G	T
Template Predicted Secondary structure												.	.	.	.	.	.	.	.
Template SS confidence
		68	.	70	.	.	.	.	.	.	.									.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.
		383	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	R	V	R	N	V	K	E	S	A	A	H	D	Y	T	L	R	E	L	K	L	S	K	V	G	Q	A	L	L	Q	G	N	T	E	R	T	V	W	Q	Y	H	F	R	T	W	P	D	H	G	V	P	S	D	P	G	G	V	L	D	F	L	E	E	V	H	H	K	Q	E	S	I	M	D	A	G	P	V	V	V	H
Query Conservation
Alig confidence																									.	.	.	.	.
Template Conservation																									.	.	.	.	.
Template Sequence		L	K	L	T	L	I	S	E	D	I	K	S	Y	Y	T	V	R	Q	L	E	L	E	N	.	.	.	.	.	L	T	T	Q	E	T	R	E	I	L	H	F	H	Y	T	T	W	P	D	F	G	V	P	E	S	P	A	S	F	L	N	F	L	F	K	V	R	E	S	G	S	L	S	P	E	H	G	P	V	V	V	H
Template Known Secondary structure													S	S											.	.	.	.	.	T	T	T																T	T				S															T	T	T	T		T	T	S
Template Predicted Secondary structure																									.	.	.	.	.
Template SS confidence
		140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.						.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.
		463	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		C	S	A	G	I	G	R	T	G	T	F	I	V	I	D	I	L	I	D	I	I	R	E	K	G	V	D	C	D	I	D	V	P	K	T	I	Q	M	V	R	S	Q	R	S	G	M	V	Q	T	E	A	Q	Y	R	F	I	Y	M	A	V	Q	H	Y	I	E	T	L	Q	R	R	I	E	E	E	Q	K	S	K	R	K
Query Conservation
Alig confidence
Template Conservation
Template Sequence		C	S	A	G	I	G	R	S	G	T	F	C	L	A	D	T	C	L	L	L	M	D	K	R	K	D	P	S	S	V	D	I	K	K	V	L	L	E	M	R	K	F	R	M	G	L	I	Q	T	A	D	Q	L	R	F	S	Y	L	A	V	I	E	G	A	K	F	I	M	G	D	S	S	V	Q	D	Q	W	K	E	L
Template Known Secondary structure			S	S	S	S	S																		S	S		G	G	G											T	T	T	S	T	T		S		S																			T	T		S	S
Template Predicted Secondary structure
Template SS confidence
		215	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.
		543	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	H	E	Y
Query Conservation
Alig confidence
Template Conservation
Template Sequence		S	H	E	D
Template Known Secondary structure			T	T	T
Template Predicted Secondary structure
Template SS confidence
		295	.	.	.

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions