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Job DescriptionP07948
Confidence100.00%DateFri May 25 10:07:35 BST 2012
Rank169Aligned Residues251
% Identity26%Templatec3mtfB_
PDB info PDB header:transferaseChain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor
Resolution2.15 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   245....250.........260.........270.........280.........290.........300........ .310.........320
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Query Sequence  ESIKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKLVRLYAV. . . . VTREEPIYIITE
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Template Sequence  RDITLLECVGKGRYGEVWRGSW. QGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITH
Template Known Secondary structure  TTTT.TT
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   206...210.........220....... ..230.........240.........250.........260.........270.........280....
 
   321........330.........340.........350.........360... ......370.........380.........390..
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Query Sequence  YMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNY. . . . . . . . IHRDLRAANVLVSESLMCKIADFGLARVI
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Template Sequence  YHEMGSLYDYLQLT. . . TLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMH
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   285....290........ .300.........310.........320.........330.........340.........350.........360.
 
   393 ......400.........410......... 420.........430.........440.........
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Query Sequence  E. . . DNEYTAREGAKFPIKWTAPEAINFGC. . . . . . FTIKSDVWSFGILLYEIVTYGKIPYPGRTN. . . . . . . . . . . . . .
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Template Sequence  SQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVAR. RMVSNGIVEDYKPPFYDVVPNDPS
Template Known Secondary structure  TTTT








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   362.......370.........380.........390.........400.........410...... ...420.........430.........440
 
   450.........460....... ..470.........480.........490.........500
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Query Sequence  . ADVMTALSQGYRMPRVEN. . . . . . CPDELYDIMKMCWKEKAEERPTFDYLQSVLDDF
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Template Sequence  FEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKI
Template Known Secondary structure  TTS






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   441........450.........460.........470.........480.........490........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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