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Job DescriptionP07948
Confidence100.00%DateFri May 25 10:07:35 BST 2012
Rank94Aligned Residues241
% Identity42%Templatec3k54A_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases.
Resolution1.94 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   238.240.........250.........260.........270.........280.........290.........300.........310.......
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Query Sequence  DAWEIPRESIKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKLVRLYAVVTREEPIYI
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Template Sequence  GSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIK. . . . . . . EFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFI
Template Known Secondary structure  GGGB

GGGSTTSS
TTT

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TT


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   393......400.........410.........420.........430... ......440.........450.........460.....
 
   318.320.........330.........340.........350.........360.........370.........380.........390.......
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Query Sequence  ITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEY
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Template Sequence  ITEYMANGCLLNYLR. EMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGFP. . . . . . . .
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TT.
GGG


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SGGG
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   473......480....... ..490.........500.........510.........520.........530.........540...
 
   398.400.........410.........420.........430.........440.........450.........460.........470.......
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Query Sequence  TAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENCPDELYDIMK
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Template Sequence  . . . . . . . . . VRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMY
Template Known Secondary structure  .........GGG





TTS

TTTTS
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   561........570.........580.........590.........600.........610.........620.........630.
 
   478.480.........490.........500...
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Query Sequence  MCWKEKAEERPTFDYLQSVLDDFYTA
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Template Sequence  SCWHEKADERPTFKILLSNILDVMDE
Template Known Secondary structure  TT
SSGGGS

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   632.......640.........650.......
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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